Results 31 to 40 of about 8,891,761 (262)

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari   +5 more
wiley   +1 more source

Spatio-temporal declines in Philippine fisheries and its implications to coastal municipal fishers’ catch and income

open access: yesFrontiers in Marine Science, 2016
The problem of overexploitation in global fisheries is well-recognized. However, published assessment of fisheries spatio-temporal trends at the national scale is lacking for many high biodiversity developing countries, which is problematic since ...
Jonathan A Anticamara, Kevin Thomas B Go
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Untying the Mediterranean Gordian Knot: A Twenty First Century Challenge for Fisheries Management

open access: yesFrontiers in Marine Science, 2017
Management of fisheries in the Mediterranean basin has often been described as a unique and complex challenge, due to their multi-specificity, the diversity of gear-types, and the number of nations involved.
Ilaria Vielmini   +2 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Sustaining Food Supply from Inland Fisheries [PDF]

open access: yes, 2011
In 2008, the total fisheries production of the region was 27,260,013 MT, of which 2,381,711 MT came from the inland capture fisheries, accounting for approximately 8.7% of the total production.

core  

ANALISIS PERSEPSI NELAYAN DALAM PENGELOLAAN SUMBERDAYA PERIKANAN BERKELANJUTAN DI TAMAN NASIONAL KARIMUNJAWA1

open access: yesTataloka, 2016
The sustainable fisheries resources management  at the Karimunjawa National Park (KNP) is a very complicated effort. One of the serious issues is that the national park was declared by government when it has been inhabited by fisherfolk community.
M Mussadun   +3 more
doaj   +1 more source

Ecosystem-based fisheries management: Perception on definitions, implementations, and aspirations. [PDF]

open access: yesPLoS ONE, 2018
Ecosystem-based fisheries management (EBFM) was developed to move beyond single species management by incorporating ecosystem considerations for the sustainable utilization of marine resources.
John T Trochta   +5 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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