Advanced Science, EarlyView.Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon +27 more
wiley +1 more source
Climate-Driven Variation in Yellowfin Tuna Productivity in the Western and Central Pacific Ocean Inferred from a State-Space Model. [PDF]
Animals (Basel)Li X, Geng Z, Cao J, Zhu J, Zhu J.
europepmc +1 more source
Herbicide Metabolic Resistance in Poaceae Plants via the GA‐GID1/DELLA‐DOF2‐P450s Module
Advanced Science, EarlyView.Plant hormone signaling modulates herbicide resistance in Echinochloa crus‐galli. The GA–DELLA–DOF2 cascade directly activates P450 detoxification genes in two Poaceae species, uncovering a core mechanism of metabolic herbicide resistance. ABSTRACT Barnyard grass (Echinochloa crus‐galli) is one of the world's most important weeds, and the evolution of ...
Junzhi Wang +6 more
wiley +1 more source
Underestimated barrier effects of ocean fronts shape global fishery distribution. [PDF]
Nat CommunXing Q +7 more
europepmc +1 more source
Sustainable Productivity Growth in Agriculture: The Role of Shifts in R&D Investments and Technology
Applied Economic Perspectives and Policy, EarlyView.ABSTRACT The objective of the paper is to evaluate the long‐term prospects of sustainable productivity growth linked to plausible assumptions on public agricultural R&D investments as the key productivity driver. Second, it investigates the role of changing R&D focus from yield maximization to input saving technologies (fertilizers and pesticides). The
Zuzana Smeets Křístková +4 more
wiley +1 more source
Marine fishery resource dynamic prediction based on CNN-XGBoost fusion model. [PDF]
Sci RepZhang M.
europepmc +1 more source
Temperature Sensitivity and Adaptation of Cereal Yields: Empirical Evidence From Italy
Applied Economic Perspectives and Policy, EarlyView.ABSTRACT This paper investigates the evolving temperature sensitivity and climate adaptation of cereal yields in Italy from 1952 to 2023, using province‐level data for maize, common wheat, and durum wheat. Employing panel data econometric methods, we estimate yield responses to heat exposure, changes in sensitivity over time, and adaptation to climate ...
Paolo Nota +2 more
wiley +1 more source
Taxation of fisheries in Kenya: neither improving management nor raising revenue? [PDF]
World Dev PerspectOcchiali G, Okello O.
europepmc +1 more source
Applied Economic Perspectives and Policy, EarlyView.ABSTRACT In recent decades, agriculture has become increasingly concentrated through horizontal mergers and acquisitions via corporate entities, and policy makers are concerned this will be exacerbated by the aging population of farm operators. To reduce market concentration in agriculture, many states have enacted policies to entice new prospective ...
Justin M. Ross +2 more
wiley +1 more source
Winter occurrence and spawning characteristics of Pacific herring (Clupea pallasii) in Jinhae Bay: An integrated survey using acoustic monitoring, gillnet sampling, and environmental DNA. [PDF]
PLoS OneYoon E, Lee YD, Lee JH, Kwon I, Lee H.
europepmc +1 more source