Results 91 to 100 of about 315,382 (293)

Total marine fishery catch for the Azores (1950–2010)

open access: yes, 2013
Official fishery statistics often fail to report what has been truly extracted from the marine environment. Therefore, in this study, we estimated illegal, unreported, and unregulated (IUU) catch in the context of a small-scale fishery (the Azores) and ...
C. Pham   +5 more
semanticscholar   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

Genetic analysis of Octopus cyanea reveals high gene flow in the South‐West Indian Ocean

open access: yesEcology and Evolution
Octopus cyanea (Gray, 1849), abundant in the South‐West Indian Ocean (SWIO), constitutes a vital resource for both subsistence and commercial fisheries.
Charles R. Treleven   +11 more
doaj   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

Marine protected areas can increase the abundance of invasive lionfish (Pterois miles)

open access: yesConservation Science and Practice
Marine protected areas (MPAs) can protect and restore marine biodiversity and fisheries, but there are concerns that they may also benefit invasive species.
Periklis Kleitou   +10 more
doaj   +1 more source

Results of the salmon fishery season in Kamchatka Region in 2023

open access: yesИзвестия ТИНРО
Results of salmon fishery in Kamchatka Region in 2023 are overviewed. Data of fishery statistics on catches of pacific salmon are presented, by fishing districts. Feasibility of fishery forecasts is estimated.
A. V. Bugaev   +3 more
doaj   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

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