Results 181 to 190 of about 403,141 (345)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Population Dynamics and Body Size Structure of the Antarctic Krill <i>Euphausia superba</i> in the Bransfield Strait and South Shetland Islands. [PDF]

Biology (Basel)
Zhao G, Li S, Yang J, Zhang G, Xu B, Liu H, Rao X, Lian P, Huang H, Li L.   +9 more
europepmc   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Five archetypes of small-scale fisheries reveal a continuum of production strategies to guide governance and policymaking. [PDF]

Nat Food
Aguión A, Basurto X, Funge-Smith S, Gorelli G, Iversen E, Mancha-Cisneros MDM, Gutierrez NL.   +6 more
europepmc   +1 more source

The development of recruitment fisheries oceanography in the United States [PDF]

, 1998
Arthur W. Kendall, Gary J. Duker
openalex   +1 more source

Ecosystem service lens reveals diverse community values of small-scale fisheries [PDF]

, 2020
Kara E. Pellowe, Heather M. Leslie
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

The Sea Lamprey (Petromyzon marinus) Invasion: The Construction of an Invasive Animal Threatening a "Healthy" Great Lakes Ecosystem. [PDF]

J Hist Med Allied Sci
Bijman V.
europepmc   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

Assessing fishery interaction on cetaceans stranded along the Italian coastline between 1986 and 2023. [PDF]

PLoS One
Pietroluongo G, Podestà M, Belluscio D, Berio E, Canonico C, Casalone C, Cavaliere F, Centelleghe C, Ceolotto L, Cocumelli C, Cozzi B, Denurra D, Di Donato A, Di Francesco G, Di Guardo G, Di Nocera F, Di Renzo L, Gavaudan S, Giorda F, Lucifora G, Marino L, Marsili L, Migliore S, Pascucci I, Pavan G, Petrella A, Pintore A, Puleio R, Rubini S, Terracciano G, Toffan A, Grattarola C, Mazzariol S.   +32 more
europepmc   +1 more source