Results 201 to 210 of about 172,580 (267)

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Genetic Dissection of Growth Traits and Identification of Candidate Genes in Japanese Flounder (<i>Paralichthys olivaceus</i>) Using Single- and Multi-Trait Genome-Wide Association Analyses. [PDF]

Biology (Basel)
Liang S, Chen A, Tuo Z, Xu J, Chen Y, Jiang L.   +5 more
europepmc   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Spatiotemporal and Interannual Habitat Variability of Three <i>Charybdis</i> Swimming Crab Species (Brachyura: Portunidae) in the Southern Yellow Sea and East China Sea. [PDF]

Biology (Basel)
Xu M, Liu Y, Li H, Zhao Q, Xue L, Wu Q, Ling J, Li H.   +7 more
europepmc   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Analysis of total and free amino acid compositions of fishery byproducts from three commonly consumed fish species in South Korea. [PDF]

Amino Acids
Han J, Hyeon JY, Lee YJ, Kim HJ, Lee E, Choi YU.   +5 more
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Reproductive Traits Revealing the Invasion and Coexistence of Two Tilapia Species in the Jinghong Reservoir of the Lower Lancang River, Southwest China. [PDF]

Animals (Basel)
Hu Z, Dong L, Li K, Zhai D, Chen Y, Liu H, Xiong F, Duan X, Liu M.   +8 more
europepmc   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Study on the Accumulation, Excretion, and Distribution of Cadmium in Mice After Dietary Exposure to Cadmium-Rich Swimming Crab <i>Portunus trituberculatus</i>. [PDF]

Foods
He R, Mo X, Li Q, Yan M, Shi Y, Sun N, Li R, Huang X, Tian L, Han F, Li S.   +10 more
europepmc   +1 more source