Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Results of the salmon fishery season in Kamchatka Region in 2023
Results of salmon fishery in Kamchatka Region in 2023 are overviewed. Data of fishery statistics on catches of pacific salmon are presented, by fishing districts. Feasibility of fishery forecasts is estimated.
A. V. Bugaev +3 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Patterns of pink salmon Oncorhynchus gorbuscha reproduction on the mainland coast of Japan Sea
Dependence of the mature pink salmon returns to the mainland coast of Japan Sea (within Primorye Region) on their parents abundance and meteorological factors at the spawning grounds is analyzed.
V. I. Ostrovsky, A. V. Lysenko
doaj +1 more source
PICES Press, Vol. 5, No. 2, July 1997 [PDF]
WG 10 Fukuoka Workshop Pacific salmon:climate-linked long-term stock fluctuations The state of the eastern North Pacific in the second half of 1996 The state of the western North Pacific in the second half of 1996 The status of the Bering Sea in ...
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This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Changes in the value of the Southeast Alaska salmon purse seine limited entry permits following two permit buy back programs [PDF]
Master's Project (M.S.) University of Alaska Fairbanks, 2014The Southeast Alaska salmon purse seine fishery (S01A) is an Alaska state waters limited entry fishery. When initially limited by the Commercial Fisheries Entry Commission in 1975, 419 permanent
Shriver, Jennifer Christine
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In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
A Changing Gulf of Maine: Investigating the Role of Benthic Water Temperature in Determining the Timing of Spiny Dogfish (Squalus acanthias) Arrival and Departure in the Gulf of Maine [PDF]
Spiny Dogfish (Squalus acanthias) is a highly migratory elasmobranch that undergoes annual migrations along the East Coast of the United States. Spiny dogfish have been studied extensively on the West Coast, but little information currently exists on the
Gallo, Benjamin Donald
core +1 more source

