Results 101 to 110 of about 20,708 (256)

PICES Press, Vol. 19, No. 1, Winter 2011 [PDF]

open access: yes, 2011
•2010 PICES Science: A Note from the Former Science Board Chairman (pp. 1-4) •2010 PICES Awards (pp. 5-7) •The First Year of FUTURE: A Progress Report (pp. 8-13) •New Chairmen in PICES (pp.

core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

esults of salmon fishery in the Khabarovsk Region in 2024

open access: yesИзвестия ТИНРО
The catch of pacific salmon in the water bodies of the Khabarovsk Territory in 2024 was initially forecasted in 51.7∙103 t. During the fishing season, one adjustment was made for pink salmon in the Primorye fishing subzone where the allowable annual ...
D. V. Kotsyuk, V. I. Ostrovsky
doaj   +1 more source

Annual report 1989 [PDF]

open access: yes, 1989
The report describes the activities of the Institute during the year 1989, which include the following: The Zambia/Zimbabwe Lake Kariba Fisheries Research and Development Project; the pilot cage culture project; cooperative development; an economic ...
Machena, C.
core  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

An observing system for the collection of fishery and oceanographic data [PDF]

open access: yesOcean Science, 2007
Fishery Observing System (FOS) was developed as a first and basic step towards fish stock abundance nowcasting/forecasting within the framework of the EU research program Mediterranean Forecasting System: Toward an Environmental Prediction (MFSTEP).
P. Falco   +5 more
doaj  

PICES Press, Vol. 20, No. 1, Winter 2012 [PDF]

open access: yes, 2012
•2011 PICES Science: A Note from the Science Board Chairman (pp. 1-6) •2011 PICES Awards (pp. 7-9) •Beyond the Terrible Disaster of the Great East Japan Earthquake (pp. 10-12) •A New Era of PICES-ICES Scientific Cooperation (p.

core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Short‐Term Management of Kelp Forests for Marine Heatwaves Requires Planning

open access: yesConservation Letters
Heatwaves are now pervasive stressors to marine ecosystems, and it is urgent to consider mitigation tools that support ecosystem resilience and persistence in the immediate future.
Jess K. Hopf   +7 more
doaj   +1 more source

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