Results 101 to 110 of about 20,852 (294)

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Variation in yellowfin tuna (Thunnus albacares) catches related to El Niño-Southern Oscillation events at the entrance to the Gulf of California [PDF]

open access: yes, 2006
Fishery catch data on yellowfin tuna (Thunnus albacares) were examined to study the effects of El Niño events between 1990 and 1999 for an area in the northeastern tropical Pacific (18−24°N, 112−104°W).
Muhlia-Melo, Arturo   +3 more
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Construction and Comparison of Machine-Learning Forecast Models of Albacore Thunnus alalunga Fishing Grounds in the South Pacific Ocean

open access: yesFishes
The traditional methods for predicting the distribution of albacore (Thunnus alalunga) fishing grounds have low performance and accuracy. Uneven sampling can result in unreasonable evaluation indicators.
Jianxiong Li   +6 more
doaj   +1 more source

Trends in marine fish catches at Pattani Fishery Port (1999-2003) [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2006
This study aims to develop statistical models for forecasting the quantity of the various types of marine fish landed at Pattani Fishery Port, allowing for trend and seasonality, using official data during 1999-2003.
Wanchamai Karntanut   +2 more
doaj  

OPTIMAL MANAGEMENT OF THE NORTHERN ATLANTIC BLUEFIN TUNA [PDF]

open access: yes
This paper analyzes the optimal management of the Northern Atlantic bluefin tuna, both eastern and western stocks. The analysis is based on a deterministic multi-gear and age-structured bioeconomic model.
Duarte, Clara Costa, Pintassilgo, Pedro
core   +1 more source

PICES Press, Vol. 21, No. 1, Winter 2013 [PDF]

open access: yes, 2013
•2012 PICES Science: A Note from the Science Board Chairman (pp. 1-6) ◾2012 PICES Awards (pp. 7-9) ◾GLOBEC/PICES/ICES ECOFOR Workshop (pp. 10-15) ◾ICES/PICES Symposium on “Forage Fish Interactions” (pp.

core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

PICES Press, Vol. 20, No. 1, Winter 2012 [PDF]

open access: yes, 2012
•2011 PICES Science: A Note from the Science Board Chairman (pp. 1-6) •2011 PICES Awards (pp. 7-9) •Beyond the Terrible Disaster of the Great East Japan Earthquake (pp. 10-12) •A New Era of PICES-ICES Scientific Cooperation (p.

core  

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

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