Results 51 to 60 of about 30,785 (306)
Seeking sustainability: Employing Ostrom's SESF to explore spatial fit in Maine’s sea urchin fishery
Achieving resource sustainability in complex social-ecological systems requires employing place-based management mechanisms congruent with the underlying temporal, spatial, and functional dynamics of the system in question.
Kimberly L Ovitz, Teresa R Johnson
doaj +1 more source
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
The configuration of fisheries policy before regional autonomy shows the hegemony of the country which adheres to the legal doctrines of collective ownership, centralism, and anti-pluralism. Since the era of regional autonomy, the provincial and district
Mashuril Anwar +2 more
doaj +1 more source
Larval Spatiotemporal Distribution of Six Fish Species: Implications for Sustainable Fisheries Management in the East China Sea [PDF]
Min Xu +9 more
openalex +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Transboundary Fisheries Management [PDF]
Abstract Malaysia’s unique geographical position, straddling across several seas within the Indian and Pacific Oceans, allows her to play an important role within the set of regional, sub-regional and bilateral arrangements for transboundary fisheries management in the Indo-Pacific theatre.
openaire +1 more source
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Strengthening Supply Chain Management Through Human Capital Development in Isolated Community-Based Fisheries [PDF]
This article examines the role of human capital development in supply chain management on Bawean Island, an isolated island in Indonesia. This study uses a soft system methodology with purposive sampling, involving in-depth interviews with 15 key ...
Rizkina Fitriana Dina +2 more
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source

