Results 51 to 60 of about 13,591 (314)

Mapping the “Supply–Demand–Flow” of Ecosystem Services for Ecosystem Management in China

open access: yesAdvanced Science, EarlyView.
This study develops a “supply–demand–flow” framework clarifies how ecosystem services move between regions by distinguishing potential and actual supply and demand. Using integrated biophysical–socioeconomic modeling, nine services in China were mapped.
Yikun Zhang   +3 more
wiley   +1 more source

ZDHHC18‐Mediated Palmitoylation of ORF3a Promotes SARS‐CoV‐2 Pathogenesis by Antagonizing TRIM16‐Mediated Ubiquitination and Proteasomal Degradation

open access: yesAdvanced Science, EarlyView.
Palmitoylation by ZDHHC18 blocks ORF3a K27‐linked ubiquitination mediated by TRIM16, thereby preventing its proteasomal degradation and strengthening viral pathogenesis. Targeting palmitoylation through a pharmacological inhibitor (2‐BP), a competitive inhibitory peptide (OPIP), or adenovirus‐mediated knockdown of ZDHHC18 expression presents a ...
Sidi Yang   +17 more
wiley   +1 more source

LEGAL AND ECONOMIC ANALYSIS OF STATE OPERATIONAL PROGRAMME FOR POLISH FISHERY SECTOR IN YEARS 2014-2020 [PDF]

open access: yesScientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development, 2016
The main aim of the article was to analyse legal and economic basis of state aid schemes for polish fishery sector in years 2045 - 2020. The paper focuses mainly on the characteristics of one operational programme “Fishery and Sea” (PO RYBY 2014-2020 ...
Jakub GOŁAŚ
doaj  

Spatial–Temporal Characteristics and Influencing Factors of Marine Fishery Eco-Efficiency in China: Evidence from Coastal Regions

open access: yes, 2023
Marine fishery is an important part of China’s maritime power strategy. Improving the ecological efficiency of marine fishery is the inevitable way to achieve the sustainable development of fishery.
Dahai Li   +3 more
core   +1 more source

Diffusion‐Based Generative Model With Scaffold‐Hopping Strategy Yields Highly Potent Bioactive Molecules

open access: yesAdvanced Science, EarlyView.
SMarT‐Diff introduces a multi‐objective generative paradigm that integrates scaffold hopping with structure‐aware scoring to enable controlled exploration beyond the training distribution. The framework consistently balances drug‐likeness, synthesizes accessibility and bioactivity, yielding chemically diverse candidates with enhanced properties.
Yuwei Yang   +8 more
wiley   +1 more source

Studying Kenai River Fisheries’ Social-Ecological Drivers Using a Holistic Fisheries Agent-Based Model: Implications for Policy and Adaptive Capacity

open access: yesFishes, 2019
Alaska’s salmon fisheries are one of the more intensely managed natural resources in the world. The state’s salmon fisheries support recreational, subsistence, and commercial harvest with multiple billions of dollars flowing into the economy,
Maxwell Franklin   +2 more
doaj   +1 more source

Combining Radiation‐Treated Tumor Vaccines With Mn‐MOF Nanoadjuvants to Amplify Radiation Induced Anti‐Tumor Immune Responses

open access: yesAdvanced Science, EarlyView.
Radiotherapy‐treated tumor membranes are integrated with Mn‐MOF nanoadjuvants to generate Mn@RM, a lymph node‐draining nanovaccine that delivers radiotherapy‐remodeled antigenic components. Mn@RM enhances dendritic cell activation, amplifies T cell‐mediated antitumor immunity, and synergizes with radiotherapy and PD‐1 blockade for combination cancer ...
Yiyu Wang   +8 more
wiley   +1 more source

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng   +14 more
wiley   +1 more source

Research on the Evolution Characteristics and Laws of China's Fishery Policy-Word Quantitative Analysis Based on the Texts of 250 Normative Documents Related to Fisheries

open access: yesHaiyang Kaifa yu guanli
China is the world's largest fishery country and also the world's largest aquaculture country. Fisheries is a very important industry in the national economy and has a significant impact on maintaining and improving the quality of people's lives ...
ZHANG Hui, YANG Huaiyu
doaj  

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