Results 91 to 100 of about 393,096 (313)

Complete mitochondrial genome of Palaemonetes sinensis and its phylogenetic consideration

open access: yesMitochondrial DNA. Part B. Resources, 2019
The aim of this study was to determine the complete mitochondrial genome (mitogenome) and the phylogenetic location of the Palaemonetes sinensis. The mitogenome was 15,736 bp in length, containing 22 transfer RNA genes (tRNAs), 13 protein-coding genes ...
Rui Li   +5 more
doaj   +1 more source

Threatened Fishes of Arkansas [PDF]

open access: yes, 1974
Intensive field collecting throughout Arkansas and a survey of literature and museum records revealed 37 fish species and subspecies in Arkansas to be threatened by human activities. Of these 37 threatened forms, seven are considered rare and endangered.
Robison, Henry W.
core   +2 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

The coarse fishes of Britain [PDF]

open access: yes, 1947
The need for research upon the coarse fishes of Britain, questions of the breeding and rearing of large numbers of young fish, more especially roach, was established back in 1937.
Hartley, P.H.T.
core  

Big fish, little fish [PDF]

open access: yesThe Journal of Thoracic and Cardiovascular Surgery, 2016
Dirk J, Varelmann, Michael N, D'Ambra
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Anadromous fish as marine nutrient vectors [PDF]

open access: yes, 2009
The tidal freshwater of Virginia supports anadromous herring (Alosa spp.) spawning runs in the spring; however, their importance as nutrient delivery vectors to the freshwater fish food web remains unknown.
Garman, Greg C.   +2 more
core  

Mountains in the Sea: Fishy Deep-sea Designs [PDF]

open access: yes
In this activity, students will focus on adaptations of fishes living in the mesopelagic and bathypelagic zones of the deep ocean. The students will learn about the physical location of deep water habitats along the Hudson Shelf Valley and in Hudson ...

core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

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