Results 101 to 110 of about 1,280,730 (308)

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Effects of pomegranate (Punica granatum) peel extract on hypoxia tolerance and biochemical markers in organs of Jian carp (Cyprinus carpio var. Jian)

open access: yesAquaculture Reports
The purpose of this study was to evaluate the effects of dietary pomegranate peel extracts (PPE) on hypoxia tolerance in carp (Cyprinus carpio var. Jian).
Haijing Liu   +9 more
doaj   +1 more source

TEMPERATURE MAPPING OF FRESH FISH SUPPLY CHAINS – AIR AND SEA TRANSPORT [PDF]

open access: bronze, 2011
Nga Mai   +5 more
openalex   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Effects of extract of Ginkgo biloba leaves on pellet quality, hypoxia tolerance and infection of Jian carp (Cyprinus carpio var. Jian) with Aeromonas hydrophila

open access: yesAquaculture and Fisheries
The effects of extracts of Ginkgo biloba leaves (EGb) on feed quality, hypoxia tolerance, and disease resistance were examined in this study. EGb were prepared by using four different solvents: aqueous, ethanol, ethyl acetate, and petroleum ether ...
Gangfu Chen   +16 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Chronic hypoxia drives the occurrence of ferroptosis in liver of fat greening (Hexagrammos otakii) by activating HIF-1α and promoting iron production

open access: yesEcotoxicology and Environmental Safety
Background: Hypoxia caused by global climate change and human activities has become a growing concern eliciting serious effect and damages to aquatic animals.
Dongxu Gao   +7 more
doaj   +1 more source

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