Results 111 to 120 of about 678,109 (371)
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi+5 more
wiley +1 more source
Nursery function rehabilitation projects in port areas can support fish populations but they remain less effective than ensuring compliance to fisheries management [PDF]
Conservation measures are implemented to support biodiversity in areas that are degraded or under anthropogenic pressure. Over the past decade, numerous projects aimed at rehabilitating a fish nursery function in ports, through the installation of artificial structures, have emerged.
arxiv
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen+17 more
wiley +1 more source
The aim of this study was to determine the effects of dietary carbohydrate levels on growth performance, feed utilization and metabolism of juvenile Yangtze sturgeon (Acipenser dabryanus).
Huantao Qu+6 more
doaj
FishNet: Deep Neural Networks for Low-Cost Fish Stock Estimation [PDF]
Fish stock assessment often involves manual fish counting by taxonomy specialists, which is both time-consuming and costly. We propose FishNet, an automated computer vision system for both taxonomic classification and fish size estimation from images captured with a low-cost digital camera.
arxiv
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane+16 more
wiley +1 more source
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas+15 more
wiley +1 more source