Results 111 to 120 of about 1,280,730 (308)

Stress in Fishes: A Diversity of Responses with Particular Reference to Changes in Circulating Corticosteroids1

Integrative and Comparative Biology, 2002
B. Barton
semanticscholar   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Hypoxia induces pyroptosis and inflammation in the liver of fat greenling (Hexagrammos otakii)

Comparative Immunology Reports
In fisheries, hypoxia stress is one of the most common environmental stresses that often cause significant harm and losses to the aquaculture industry.
Yu Zhan, Dongxu Gao, Lei Peng, Dandan Cui, Guohan Li, Shengnan Cao, Yan Chen, Zhuang Xue, Wei Wang   +8 more
doaj   +1 more source

Fish‐Oil Fat Emulsion Supplementation Reduces the Risk of Retinopathy in Very Low Birth Weight Infants

, 2013
Dorota Pawlik, Ryszard Lauterbach, Maria Walczak, Joanna Hurkała, Michael P. Sherman   +4 more
openalex   +2 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Effects of dietary fermented attachments of suspension cage as a replacement for sea mud on growth and intestinal health of sea cucumber Apostichopus japonicus

Aquaculture Reports
In the suspension cage culture process, regular cleaning to remove epiphytic organisms from the cage is essential to prevent economic losses due to the sinking of the cage.
Zhixu Guo, Zuxiang Peng, Yuntian Zhang, Xiangyu Meng, Di Wu, Rongwei Zhang, Yi Chen, Yuehan Wang, Xiaoran Zhao, Tongjun Ren, Yuzhe Han   +10 more
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Replacing sea mud with attachment of suspension cage can improve growth and gut health for sea cucumber Apostichopus japonicus

Frontiers in Marine Science
During the suspension cage culture procedure, a substantial quantity of attachments from the suspension cage will amass in the tidal flats, resulting in environmental pollution and resource wastage.
Zhixu Guo, Zhixu Guo, Xiangyu Meng, Xiangyu Meng, Yuntian Zhang, Yuntian Zhang, Di Wu, Di Wu, Rongwei Zhang, Rongwei Zhang, Xiaoran Zhao, Tongjun Ren, Yuzhe Han, Yuzhe Han   +13 more
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Influences of water velocity on ovarian maturation and antioxidant capacity in adult grass carp (Ctenopharyngodon idellus)

Frontiers in Marine Science
Ecological operation of hydraulic engineering is essential for the conservation of fishery resources. Water velocity is known to affect the spawning of fishes delivering drifting eggs.
Tingting Shu, Tingting Shu, Jing Yang, Jing Yang, Zhaoxi Yu, Zhaoxi Yu, Kan Xiao, Kan Xiao, Hongtao Huang, Hongtao Huang, Lingquan Dai, Lingquan Dai, Zhan Yin, Wei Jiang, Wei Jiang   +14 more
doaj   +1 more source