Results 41 to 50 of about 1,577,442 (403)

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Molecular Identification and Functional Characterization of LC-PUFA Biosynthesis Elongase (elovl2) Gene in Chinese Sturgeon (Acipenser sinensis)

Animals
Elongases of very-long-chain fatty acids (Elovls) are critical rate-limiting enzymes that are involved in LC-PUFA biosynthesis through catalyzing the two-carbon elongation of a pre-existing fatty acyl chain. Thus far, several Elovls have been extensively
Haoze Ding, Xuetao Shi, Zhengyong Wen, Xin Zhu, Pei Chen, Yacheng Hu, Kan Xiao, Jing Yang, Tian Tian, Dezhi Zhang, Shuqi Wang, Yang Li   +11 more
doaj   +1 more source

Effects of dietary carbohydrate on growth, feed utilization, hepatic glucose and lipid metabolism in endangered Yangtze sturgeon (Acipenser dabryanus)

Aquaculture Reports, 2022
The aim of this study was to determine the effects of dietary carbohydrate levels on growth performance, feed utilization and metabolism of juvenile Yangtze sturgeon (Acipenser dabryanus).
Huantao Qu, Wei Ke, Zhihao Wen, Baifu Guo, Xuebao Lu, Yu Zhao, Yuanjin Yang   +6 more
doaj   +1 more source

Fish and freshwater crayfish communities of the Brunswick and Preston Rivers [PDF]

, 2006
The Leschenault Inlet, located on the Swan Coastal Plain near Bunbury, is the estuary of the Brunswick, Collie, Preston and Ferguson Rivers. There is a considerable amount of information detailing the fish fauna of the Leschenault Inlet with Potter et al.
Beatty, S., Morgan, D.
core   +1 more source

Fish and Fishing in the Roman World [PDF]

Journal of Maritime Archaeology, 2018
This article focuses on two aspects related to fish and fishing. It first discusses the social context for the consumption of preserved and fresh fish, showing that generally consumption of certain types of fresh fish conferred status, whereas consumption of preserved fish, being more affordable, was attested across social strata.
openaire   +2 more sources

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

Behavioural individuality in clonal fish arises despite near-identical rearing conditions

Nature Communications, 2017
Genetically-identical animals experiencing the same environmental conditions should develop, in theory, identical behavioral traits. However, Bierbachet al.
David Bierbach, Kate L. Laskowski, Max Wolf   +2 more
doaj   +1 more source

CCT4 promotes tunneling nanotube formation

FEBS Letters, EarlyView.
Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto, Akiko Asada, Taro Saito, Kanae Ando   +3 more
wiley   +1 more source

Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes

FEBS Letters, EarlyView.
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji, Yuko Katayama, Nanase Arata, Mariko Sasaki   +3 more
wiley   +1 more source

Potential Targets and Signaling Mechanisms of Cinnamaldehyde Enhancing Intestinal Function and Nutritional Regulation in Fat Greenling (Hexagrammos otakii)

Aquaculture Nutrition
Cinnamaldehyde is an ideal feed additive with good immune enhancement and anti-inflammatory regulation effects. However, the anti-inflammatory regulation mechanism in fat greenling (Hexagrammos otakii, H. otakii) remains unclear.
Yixin Gu, Yu Zhan, Yafeng Guo, Wenyuan Hua, Xin Qi, Zhizhi Gu, Shengnan Cao, Yan Chen, Zhuang Xue, Wei Wang   +9 more
doaj   +1 more source