Results 51 to 60 of about 81,386 (268)

Hindering the biofilm of microbial pathogens and cancer cell lines development using silver nanoparticles synthesized by epidermal mucus proteins from Clarias gariepinus

BMC Biotechnology
Scientists know very little about the mechanisms underlying fish skin mucus, despite the fact that it is a component of the immune system. Fish skin mucus is an important component of defence against invasive infections. Recently, Fish skin and its mucus
Ahmed N. Alabssawy, Mohammed Abu-Elghait, Ahmad M. Azab, Hassan M. M. Khalaf-Allah, Abdelrahman S. Ashry, Ahmed O. M. Ali, Abu-Bakr A. A. Sabra, Salem S. Salem   +7 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

The Evolution of Three Schizothoracinae Species from Two Major River Systems in Northwest China Based on Otolith Morphology and Skeletal Structure

Biology
Schizothoracinae species are the largest group of Cypriniformes that readily adapt to the natural conditions of the Qinghai-Tibet Plateau. This group has habitat characteristics and distribution patterns centered on the Qinghai-Tibet Plateau.
Chengxin Wang, Linghui Hu, Yong Song, Haoyang Xie, Liting Yang, Gulden Serekbol, Bin Huo, Shengao Chen   +7 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

Effects of Dietary ARA/EPA Ratio on Growth Performance, Antioxidant Capacity and Lipid Metabolism-Related Genes of Juvenile Fat Greenling (Hexagrammos otakii)

Fishes
Essential fatty acids are extremely important nutrients in the diet of fish, and the balance between arachidonic acid (ARA) and eicosapentaenoic acid (EPA) is crucial for the healthy growth of fish.
Fengzhi Lu, Yafeng Guo, Dandan Cui, Wenyuan Hua, Shuai Wang, Lei Peng, Yan Chen, Jian Han, Wei Wang   +8 more
doaj   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

FEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring, Jan de Jonge, Hans‐Peter Braun, Nils Rugen   +3 more
wiley   +1 more source

Synthesis of biosafe spirulina-derived carbon dots and their fluorescence imaging in zebrafish

Results in Chemistry
Carbon dots (CDs) have emerged as promising fluorescent nanomaterials owing to their superior optical properties and favorable biocompatibility. In the present study, environmentally friendly CDs were synthesized from spirulina via a hydrothermal ...
Yue Wang, Zhizhi Gu, Jingyi Dong, Cunguang Liu, Jie Zhu, Zixu Wang, Jiaying Li, Meichen Lu, Jian Han, Shengnan Cao, Zhuang Xue, Yan Chen, Liyong Chen, Wei Wang   +13 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Lycium barbarum Polysaccharides Alleviate High-Fat Diet–Induced Lipid Metabolism Disorder in Takifugu obscurus

Aquaculture Nutrition
Excessive dietary fat intake disrupts lipid metabolism and induces oxidative stress and inflammation in aquatic species, impairing growth and health. In Takifugu obscurus, a widely cultivated fish species in China, fat predominantly accumulates in the ...
Shenglin Yue, Fuqiang Wang, Zixiang Lin, Yiyang Huang, Tinghao Ma, Yingkang Sun, Yuzhe Han, Tongjun Ren, Xiaoran Zhao, Xiuli Wang   +9 more
doaj   +1 more source