Results 41 to 50 of about 856,392 (338)

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

Livelihood features of small scale fishing communities : A case from Singkarak Lake, west Sumatra Indonesia [PDF]

open access: yes, 2010
While millions of poor still depend on small scale freshwater fisheries to earn a meager leaving, the sector shows overall decline in catches over recent years throughout South East Asia. Among few other causes, overfishing is often pointed out as a main
Perret, Sylvain, Yuerlita,
core  

Environmental and fishing effects on the dynamic of brown tiger prawn (Penaeus esculentus) in Moreton Bay (Australia)

open access: yes, 2013
This analysis of the variations of brown tiger prawn (Penaeus esculentus) catch in the Moreton Bay multispecies trawl fishery estimated catchability using a delay difference model. It integrated several factors responsible for variations in catchability:
Courtney, Anthony J.   +2 more
core   +1 more source

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

open access: yesFEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi   +5 more
wiley   +1 more source

PERBEDAAN PENDAPATAN PENANGKAPAN IKAN ANTARA KAPAL PURSE SEINE DAN KAPAL LINEFISHING (Sekoci) DI LOKASI RUMPON DI PERAIRAN TELUK PRIGI KECAMATAN WATULIMO KABUPATEN TRENGGALEK PROPINSI JAWA TIMUR [PDF]

open access: yes, 2007
This research was done at Prigi area Watulimo Sub-district Trenggalek residence at February 5th to 10th 2007.\ud This research aimed to find out the difference of fishing income at rumpon location with ‘purse seine’ and ‘line fishing’ tool by using ...
SUBEKHANA, EDY
core  

PERSPECTIVES REGARDING THE DEVELOPMENT OF INTENSIVE REARING TECHNOLOGY FOR SILURUS GLANIS SPECIES IN ROMANIA

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
This work represents the early development of a new rearing system of species Silurus glanis in Romania, meaning the growth cycle of biological material from 1 g/ex. - fry to 1.2 kg / ex. - average weight.
MARILENA TALPEŞ   +3 more
doaj  

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

open access: yesFEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen   +2 more
wiley   +1 more source

The role of women in fish processing: handling and marketing in Kainji Lake basin [PDF]

open access: yes, 2005
The study assessed the contribution of women in fish handling, processing and marketing in Kainji Lake basin. Structured questionnaires were administered to three fishing villages selected at random.
Bako, W.S.
core  

Analyzing the Impacts of Climate Change on the Hydrological Regime and Aquatic Biodiversity of the Danube River

open access: yesBulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Animal Science and Biotechnologies
Climate change presents considerable challenges to global ecosystems, particularly freshwater environments like the Danube River. This study investigates the variability in hydrological and physico-chemical parameters of the Danube River, alongside ...
Desimira Maria STROE   +5 more
doaj   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

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