Results 51 to 60 of about 254,318 (261)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Psychological Features of Seamen's Activity in Emergency Situations [PDF]

open access: yesTransNav, 2010
The rendered material will help to form a clear view of psychological features of human activity in situations concerning increased danger to a person?s existence.
Vitaliy Bondarev, Olga M. Bondareva
doaj  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

[Partner] Global Fishing Watch

open access: yes, 2021
Global Fishing Watch seeks to increase transparency of human activity at ...
Global Fishing Watch
core  

Strategic Study for Sustainable Development of Freshwater Aquaculture in Camagüey

open access: yesRevista de Producción Animal, 2018
A strategic study of biological-fishing behavior of the main variables determined for extensive freshwater aquaculture was made in facilities of the Camagüey Fishing Company, province of Camagüey, Cuba.
Pedro Enrique Ramírez Fernández   +2 more
doaj  

Methodological Approaches to the Design of Business Games and Definition of the Marine Specialist Training Content [PDF]

open access: yesTransNav, 2012
Knowledge owned by marine specialists demand only in rare cases of extreme navigation situations. In this regard, the development of training game methods for actions in such situations is a very actual problem. The complex of professional business games
Sergey Moyseenko, Leonid Meyler
doaj  

Fishers perceptions of ecosystem service change associated with climate‐disturbed coral reefs

open access: yesPeople and Nature, 2021
Understanding ecosystem service change necessitates an understanding of the social and ecological dimensions of ecosystem services and how they contribute to the well‐being of different people. These empirical research gaps persist across the tropics and
Anna J. Woodhead   +7 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Reproductive aspects of Acanthurus chirurgus (Perciformes: Acanthuridae) captured by the artisanal fleet operating in Itamaracá Island, Pernambuco, Brazil

open access: yesScientia Marina
This study examined the reproductive biology of Acanthurus chirurgus through monthly collections from May 2016 to May 2018. A total of 505 specimens (317 males, 188 females) were analysed, with males having a larger total length than females (32.0 cm vs.
Paulo R. Souza-Almeida   +4 more
doaj   +1 more source

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