Results 151 to 160 of about 388,975 (339)
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Assessing Northeast Florida Offshore Blue Crab Fishing Effort within Florida’s State Waters [PDF]
Samantha L. Ehnert‐Russo +2 more
openalex +1 more source
Fisheries Instrument Choice under Uncertainty [PDF]
This paper uses data from an actual fishery to construct a tractable and dynamic model to compare expected profit and its variance, optimal stock size, optimal harvest rate and optimal fishing effort under different management regimes under uncertainty ...
R. Quentin Grafton +2 more
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Modelling Multi-Species Targeting of Fishing Effort in the Queensland Coral Reef Fin Fish Fishery [PDF]
L. Rich Little +8 more
openalex
Estimation of Production Functions on Fishery: A Danish Survey [PDF]
The fishing fleet and the component parts of effort and production can be de-scribed and analysed in different ways. As an example, the fishing fleet can be described using a list of different production function specifications.
Ayoe Hoff +2 more
core +1 more source
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
A check of traditional parameters based on fishing effort in the surface fishery of juvenile albacore in the Northern Atlantic [PDF]
A. González-Garcés-Santiso +1 more
openalex

