Results 51 to 60 of about 387,580 (274)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

HyFish: hydrological factor fusion for prediction of fishing effort distribution with VMS dataset

open access: yesFrontiers in Marine Science
Predicting fishing effort distribution is crucial for guiding fisheries management in developing effective strategies and protecting marine ecosystems. This task requires a deep understanding of how various hydrological factors, such as water temperature,
Yuqi Shi   +6 more
doaj   +1 more source

Species Trends in Sport Fisheries, Monterey Bay, Calif., 1959-86 [PDF]

open access: yes, 1995
Three surveys spanning 28 years were examined for changes in species caught by recreational fishermen from small boats (skiffs) and commercial passenger fishing vessels (CPFV's) in California's Monterey Bay region.
Mason, Janet E.
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Bait shrimp fishery of Biscayne Bay [PDF]

open access: yes, 1985
A small but valuable live bait shrimp fishery has existed in Biscayne Bay since at least the early 1950s. In recent years there has been increasing pressure from recreational fishing and environmental groups to eliminate this fishery from the Bay because
Berkeley, Steven A.   +2 more
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Practical measures for sustainable shark fisheries: Lessons learned from an Indonesian targeted shark fishery. [PDF]

open access: yesPLoS ONE, 2018
Overfishing is a major threat to the survival of shark species, primarily driven by international trade in high-value fins, as well as meat, liver oil, skin and cartilage.
Irfan Yulianto   +9 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The Bait Purse-seine Fishery for Atlantic Menhaden, Brevoortia tyrannus, in the Virginia Portion of Chesapeake Bay [PDF]

open access: yes, 2011
Through the mid 1990’s, the bait purse-seine fishery for Atlantic menhaden, Brevoortia tyrannus, in the Virginia portion of Chesapeake Bay was essentially undocumented.
O'Bier, Bradley, Smith, Joseph W.
core  

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