Results 71 to 80 of about 1,360,631 (252)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
EFFORT DYNAMICS AND ALTERNATIVE MANAGEMENT POLICIES FOR THE SMALL PELAGIC FISHERIES OF NORTHWEST PENINSULAR MALAYSIA [PDF]
The dynamics of fish stocks are an important consideration in determining appropriate fishery management policy. Equally crucial are the dynamics of fishing effort.
Heaps, Terry, Yew, Tai Shzee
core
Trends and Environmental Drivers of Marine Fish Landings in Cuba’s Most Productive Shelf Area
FishesMarine finfish landings in Cuba have decreased during the last 30 years. However, in Cuba’s most productive fishing region, certain species, including rays, herrings, and snappers, have had increased landings over the past decade. Despite these anomalies,
Yunier Olivera-Espinosa +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
FISHING BEHAVIOR AND THE LENGTH OF THE FISHING SEASON [PDF]
The basic hypothesis of this paper is that the amount of fishing that a fish harvester undertakes during a year is not determined entirely by circumstances which are exogenous to the fisher, such as weather conditions and resource availability, but is ...
Roy, Noel
core
Nauplius, 2018 The century-old mangrove crab Ucides cordatus Linnaeus, 1763 harvesting is a traditional activity of Northeastern Brazilian coastal communities, who use it as food, source of income and cultural reference.
Fabiola Helena dos Santos Fogaça +7 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
THE ECONOMICS OF ILLEGAL FISHING: A BEHAVIORAL MODEL [PDF]
This paper analyzes the microeconomic behavior of fishers responding to imperfectly enforced regulations through illegal fishing and efforts to avoid detection.
Cross, Melvin L. +2 more
core
, 2017 The file "Fishing Effort" contains data about the fishing effort during the angling phase of the experiment. The file contains the site that was fished, the beginning time and the end time of a stretch of angling, the rod used and the bait ...
Christopher T. Monk (7071638) +3 more
core +1 more source