Results 71 to 80 of about 387,580 (274)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Monitoring mangrove crab Ucides cordatus Linnaeus, 1763 (Crustacea: Ucididae) landing in the Parnaíba River Delta: fishing characteristics, social and economic aspects

Nauplius, 2018
The century-old mangrove crab Ucides cordatus Linnaeus, 1763 harvesting is a traditional activity of Northeastern Brazilian coastal communities, who use it as food, source of income and cultural reference.
Fabiola Helena dos Santos Fogaça, Lissandra Corrêa Fernandes-Góes, Liliana Oliveira Souza, Kesley Paiva da Silva, João Marcos de Góes, Alitiene Moura Lemos Pereira, Monica Giacometti Mai, João Avelar Magalhães   +7 more
doaj   +1 more source

Whale-watching and Herring Fishing: Joint or Independent Production? [PDF]

The effects of "localized depletion" of a pelagic fishery (herring) on a non-extractive marine activity (tourism) are investigated. Proponents of the localized depletion theory claim that intense fishing effort can lead to areas that are unsuitable for ...
Lee, Min-Yang A.
core   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Status of demersal fishery resources in the Gulf of Thailand [PDF]

Data from trawl surveys (1961 - 95) and annual production statistics (1971 - 95) were used to examine the status of demersal fishery resources in the Gulf of Thailand.
Amnuay Kongprom, Eiamsa-Ard, M., Mala Supongpan, Pakjuta Khemakorn   +3 more
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Trends and Environmental Drivers of Marine Fish Landings in Cuba’s Most Productive Shelf Area

Fishes
Marine finfish landings in Cuba have decreased during the last 30 years. However, in Cuba’s most productive fishing region, certain species, including rays, herrings, and snappers, have had increased landings over the past decade. Despite these anomalies,
Yunier Olivera-Espinosa, Yandy Rodríguez-Cueto, Fabián Pina-Amargós, Francisco Arreguín-Sánchez, Manuel J. Zetina-Rejón, Kendra Karr, Pablo del Monte-Luna   +6 more
doaj   +1 more source

Optimal number ofsites in multi-site fisheries with fish stock dependent migrations

Mathematical Biosciences and Engineering, 2011
We present a stock-effort dynamical model of a fishery subdivided intofishing zones. The stock corresponds to a fish population moving betweenthese zones, on which they are harvested by fishing fleets. We consider alinear chain of identical fishing zones.
Ali Moussaoui, Pierre Auger, Christophe Lett   +2 more
doaj   +1 more source

Southern California private-boat sport fishermen: how familiar are they with the sport fishing regulations? [PDF]

, 1980
Anglers frequently violate sport fishing regulations out of ignorance, by mistake, or by deliberate action. To determine whether unfamiliarity with the regulations plays a major part in this problem, we asked anglers on privately-owned, trailerable ...
Wine, Vickie L.
core