Results 71 to 80 of about 64,329 (290)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

L’estran : un espace fantasmé

Les Nouvelles de l’Archéologie, 2019
The seashore has long been considered by archaeologists as an area devoted to a survey archaeology. However, the french Atlantic/Channel/North Sea foreshore shows traces of many sites or implements linked with onboard fishing and the exploitation of ...
Cyrille Billard, Marie-Yvane Daire, Catherine Dupont, Olivia Hulot, Gregor Marchand   +4 more
doaj  

Fishing ship trajectory prediction considering trajectory behavior characteristics

Journal of Ocean Engineering and Science
Understanding and accurately predicting the trajectory changes of fishing ships is of great significance for effectively preventing collisions between merchant and fishing ships and enhancing the safety supervision of fishing ships.
Jianwen Ma, Zhaojun Chen, Jingru Yuan, Jinyu Li, Guoxin Liu   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Ecosystem approach to coral fish management domain fishing techniques at PPI Ie Meulee, Sabang City

Depik Jurnal
The study was conducted froam June to July 2024 located in PPI Ie Meulee, Sukajaya District, Sabang city, Aceh Province. The data collection methods include primary data (interviews and questionnaire) and secondary data (from relavant institutions and ...
Ayu Sriwulanda, Alvi Rahmah, Imelda Agustina, Ratna Mutia Aprilla, Abel Muammar Mesha   +4 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Utilization Status and Trend Analysis of Antarctic Krill Fishing and Processing Ships

Haiyang Kaifa yu guanli, 2022
Antarctic krill is widely distributed in Antarctic waters, with rich resource reserves. It is the largest single catching biological resource in the world′s oceans.
Xinyue ZHANG, Hanfeng ZHENG, Qin LIU, Wanyong WANG, Ganjing QIN   +4 more
doaj  

Fishing Methods at a Glance

Fishing Methods at a Glance is an educational visual resource developed by VeriFish to support understanding of how seafood is harvested from the ocean. The poster presents eight commonly used fishing gear types – pelagic trawl, bottom trawl, pole-and-line, longlines, purse seine nets, boat seine nets, gillnets and entangling nets, and fykes, traps ...
De Sanctis, Nicole, Salvo Borda, Ixai, Absil, Christine, Astley, Sian, Pittonet Gaiarin, Sara, Boonstra, Michelle   +5 more
openaire   +2 more sources

An investigation of factors related to the bycatch of small cetaceans in fishing gear [PDF]

, 2011
The bycatch of cetaceans in fishing gear is considered to be one of the biggest conservation threats to these species. Gear modifications have the potential to reduce these bycatches in global fisheries but there is little available information on how ...
Mackay, Alice I.
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source