Results 1 to 10 of about 30,071 (160)

A bottom-up approach to find lead compounds in expansive chemical spaces [PDF]

open access: yesCommunications Chemistry
Drug discovery starts with the identification of a “hit” compound that, following a long and expensive optimization process, evolves into a drug candidate. Bigger screening collections increase the odds of finding more and better hits.
Álvaro Serrano-Morrás   +19 more
doaj   +2 more sources

Microwave-assisted synthesis of new triangulenium dyes for lifetime imaging microscopy (FLIM) [PDF]

open access: yesScientific Reports
We introduce a novel microwave-assisted method for the rapid and efficient synthesis of triangulenium dyes, enabling the creation of a broader range of these fluorophores, which are characterized by very long fluorescence lifetimes. We prepared different
Carmen Viedma-Barba   +9 more
doaj   +2 more sources

Características físicas, fisicoquímicas y sensoriales de granos de cacao (Theobroma cacao) variedad FTA-4 cosechado en el departamento de Arauca evaluado en condiciones de fermentación y secado variables.

open access: yesEntre Ciencia e Ingeniería, 2023
Las nuevas variedades de cacao como el clon FTA-4 proveniente del departamento de Arauca - Colombia, poseen una insipiente revisión científica, entonces se permitió evaluar el comportamiento del beneficio de granos. En la fase de fermentación se analizó
Jhon Esteban Armenta Roncancio   +3 more
doaj   +1 more source

La “escritura continua” como posibilidad o del no-equilibrio al equilibrio en el universo poético de Enrique Verástegui

open access: yesLiteratura: Teoría, Historia, Crítica, 2020
En esta nota me propongo mostrar la articulación del “universo poético” del poeta peruano Enrique Verástegui, desde su propia reflexión. Para ello, trazo una relación entre la búsqueda de estructuras poéticas de Verástegui y las estructuras disipativas ...
Tania Favela Bustillo
doaj   +1 more source

Spectroelectrochemistry and photoelectrochemistry of electrodeposited ZnO nanorods

open access: yesElectrochemical Science Advances, 2022
The electrodeposition of nanostructured semiconductors with tunable properties is of vital importance to develop optoelectronic devices. In this work, we introduce a novel synthesis protocol involving a multiple pulse electrodeposition nucleation stage ...
Cecilia I. Vázquez   +4 more
doaj   +1 more source

Domoic Acid Oxidative Effects on the Microalgae Phaeodactylum tricornutum

open access: yesLife, 2023
Domoic acid (DA) is a natural occurring marine biotoxin. Oxidative stress generation due to DA exposure was reported in animals, but little is known on the phytoplankton community.
Joaquin Cabrera   +2 more
doaj   +1 more source

Rat liver antioxidant response to iron and copper overloads [PDF]

open access: yes, 2014
The rat liver antioxidant response to Fe and Cu overloads (0–60 mg/kg) was studied. Dose- and time-responses were determined and summarized by t1/2 and C50, the time and the liver metal content for half maximal oxidative responses.
Boveris, Alberto Antonio   +8 more
core   +1 more source

Excited States of Proton-bound DNA/RNA Base Homo-dimers: Pyrimidines [PDF]

open access: yes, 2014
We are presenting the electronic photo fragment spectra of the protonated pyrimidine DNA bases homo-dimers. Only the thymine dimer exhibits a well structured vibrational progression, while protonated monomer shows broad vibrational bands. This shows that
Adesokan A. a   +55 more
core   +5 more sources

La moderna alquimia: la industria química

open access: yesRevista Facultad de Ingeniería Universidad de Antioquia, 2002
Se hace un breve resumen de la evolución de la química desde la más remota antigüedad, pasando por la alquimia, la iatroquímica, la electroquímica, la teo­ría atómica y los descubrimientos de los siglos XVII, XVIII, XIX y XX, que desembocaron en la ...
Asdrúbal Valencia-Giraldo
doaj   +1 more source

Inclusion of [H3PW12O40] and [H4SiW12O40] into a silica gel matrix via "sol-gel" methodology [PDF]

open access: yes, 2017
Indexación: Web of Science; Scopus.Here we report the inclusion of two Keggin Polyoxometalates (POMs), [H3PW12O40] and [H4SiW12O40], into silica gels by integrating them during the preparation of the SiO2 matrix via "sol-gel" methods.
Carey, D.M.   +4 more
core   +1 more source

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