Results 81 to 90 of about 11,867 (161)
Ecology and Evolution, Volume 16, Issue 8, August 2026.When cultures of the microorganism Tetrahymena pyriformis are transferred to environments with different temperature and resource levels, the phenotypic traits of the microorganisms—including cell size, metabolic rate, and movement speed—change.
Andrea Perna +3 more
wiley +1 more source
EPJ Web of Conferences, 2013 For experiments aimed at the study of spontaneous fission of transfermium nuclei improvements in the focal plane detector system of recoil separator VASSILISSA have been made.
Svirikhin Alexandr +15 more
doaj +1 more source
MedComm, Volume 7, Issue 8, August 2026.Rab8a‐dependent tethering of lipid droplets to mitochondria sustains fatty acid oxidation and cardiomyocyte metabolic flexibility under normoxia. During hypoxia/reoxygenation, Rab8a loss and PLIN5‐associated lipophagy uncouple lipid breakdown from mitochondrial utilization, driving lipotoxicity and cell death.
Jialing Tang +6 more
wiley +1 more source
SIRT Family: Biological Functions and Therapeutic Targets
MedComm, Volume 7, Issue 8, August 2026.SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang +9 more
wiley +1 more source
Aging Cell, Volume 25, Issue 8, August 2026.Age‐related downregulation of AcSirt2 impairs mitochondrial homeostasis in old bees. AcSirt2‐mediated deacetylation of FOXO enhances transcriptional activity, upregulating antioxidant enzymes (SOD, CAT) and promoting PINK1/Parkin‐mediated mitophagy. This pathway facilitates autophagosome formation and clearance of damaged mitochondria, reducing ROS ...
Qiang Ma +8 more
wiley +1 more source
The GLP‐1–Mitochondria Axis in Metabolic Aging
Aging Cell, Volume 25, Issue 8, August 2026.Glucagon‐like peptide‐1 receptor agonists engage AMPK–PGC‐1α signaling to remodel mitochondrial biogenesis, dynamics, and quality control, but downstream effects are context‐dependent and tissue‐specific rather than uniformly receptor‐proximal. Whether this proposed mitochondria‐incretin axis reflects a novel geroscience mechanism or indirect metabolic
Renin Chang +3 more
wiley +1 more source
The FEBS Journal, Volume 293, Issue 16, Page 5041-5066, August 2026.Exercise‐related microRNAs cel‐miR‐249‐3p and cel‐miR‐77‐5p in C. elegans regulate lifespan, fitness, mitochondrial morphology and membrane potential. Although lacking direct mammalian orthologs, H2O2‐induced microRNAs mmu‐miR‐181a‐5p and mmu‐miR‐378a‐3p regulate myogenesis, autophagy, mitochondrial content and respiration in murine myoblasts ...
Qin Xia +7 more
wiley +1 more source
Therapeutic potential of spexin in diabetic neuropathy: Insights from in vitro and in vivo models
Experimental Physiology, Volume 111, Issue 8, Page 3800-3817, 1 August 2026.Abstract The present study investigated the therapeutic potential of spexin (SPX) on both in vitro and in vivo models of diabetic neuropathy (DN). A total of 40 male BALB/c mice were randomly allocated into four experimental groups (n = 10 per group): a normoglycaemic control, an untreated DN group and two SPX treatment groups (DN+SPX‐12.5 and DN+SPX ...
Mehmet Refik Bahar +5 more
wiley +1 more source
The Journal of Physiology, Volume 604, Issue 16, Page 6704-6730, 15 August 2026.Abstract figure legend This review utilized animal models of complicated human pregnancies that result in reduced fetal nutrient or oxygen delivery, or combined nutrient and oxygen delivery, to elucidate their independent and/or synergistic contributions to the development of high‐risk cardiac phenotypes.
Melanie R. Bertossa +8 more
wiley +1 more source
CaV1.2 dynamics in native male arterial myocytes
The Journal of Physiology, Volume 604, Issue 15, Page 6302-6323, 1 August 2026.Abstract figure legend Proposed model of microtubule‐dependent CaV1.2 reorganization in vascular disease. Schematic illustration of microtubule‐mediated delivery and stabilization of CaV1.2 channels into enlarged plasma membrane clusters in response to Ang II or hyperglycaemia, promoting cooperative gating and enhanced Ca2+ influx. Abstract L‐type CaV1.
Miguel Martin‐Aragon Baudel +9 more
wiley +1 more source