Results 51 to 60 of about 4,241 (177)

Perioperative utilization of JAK inhibitors in Perianal Fistulizing Crohn's disease

open access: yesJPGN Reports, Volume 7, Issue 1, Page 110-113, February 2026.
Abstract With the recent approval of small molecule drugs such as upadacitinib in adult inflammatory bowel disease (IBD), their utilization is becoming more common; however, there is limited data on perioperative risks or optimal timing of cessation and resumption to mitigate flares. Current recommendations suggest holding these medications for 14 days
Alexander Lyons   +2 more
wiley   +1 more source

Diagnosis and Management of a Cryptoglandular Actinomycotic Fistula-in-Ano: An Update on 7 New Cases and a Review of the Literature [PDF]

open access: yesAnnals of Coloproctology, 2018
Purpose Primary anal actinomycosis of cryptoglandular origin, a rare cause of anal suppurative disease, requires specific management to be cured. The aims of this retrospective study were to describe clinical, morphological, and microbiological features ...
Axel Egal   +6 more
doaj   +1 more source

Effectiveness of Video-assisted Anal Fistula Treatment (VAAFT) and Its Adjuncts in the Treatment of a Cohort of Patients with Recurrent Fistula-in-ano

open access: yesAmrita Journal of Medicine, 2021
Recurrence of disease after surgery for fistula occurs in approximately 30%–40% of patients. Treatment of a recurrent fistula has an increased risk of failure and further recurrence.
Vaishnavi Gunasekharan   +5 more
doaj   +1 more source

Isolated anal tuberculosis presenting as an anal fistula in an immunocompetent child

open access: yesJPGN Reports, Volume 7, Issue 1, Page 47-50, February 2026.
Abstract Extra‐pulmonary tuberculosis accounts for less than 15% of all tuberculosis cases, while intestinal tuberculosis accounts for less than 1% of extra‐pulmonary forms of the disease. Abdominal organ involvement is more common, but extension to the ano‐perineal region is extremely rare.
Mariam Lagrine   +4 more
wiley   +1 more source

Autologous Adipose Tissue Injection as Treatment for Ileoanal Pouch‐Related Fistulae

open access: yesUnited European Gastroenterology Journal, Volume 14, Issue 1, February 2026.
ABSTRACT Background Ileal pouch‐anal anastomosis (IPAA) is a standard surgical procedure for ulcerative colitis (UC) and familial adenomatous polyposis. However, pouch‐related fistulae (PRF) are a significant complication. There is no consensus on the optimal treatment for PRF.
Hayder Alqaisi   +3 more
wiley   +1 more source

Cerebral Edema Secondary to Heavy Metal Toxicity From Siddha Medicine: A Case Report and Case‐Based Review

open access: yesCase Reports in Neurological Medicine, Volume 2026, Issue 1, 2026.
Background Traditional Indian medicine has been used to treat a variety of illnesses for centuries. However, there are existing concerns surrounding its heavy metal content. Amongst the different systems of traditional Indian medicine, Ayurvedic medicine has been most frequently implicated in heavy metal toxicity, while Siddha medicine has only very ...
Zhibin Tan   +8 more
wiley   +1 more source

Tea and Blood–Brain Barrier Homeostasis: Potential Mechanisms and Improvement Strategies

open access: yesFood Frontiers, Volume 6, Issue 6, Page 2673-2697, November 2025.
Abstract The blood–brain barrier (BBB), a selective interface regulating cerebral substance exchange, plays a crucial role in maintaining cognitive function and metabolic balance. While tea consumption has been traditionally associated with health benefits, its specific effects on BBB integrity warrant systematic investigation. This review demonstrates
Rongbosen Yue   +5 more
wiley   +1 more source

Congenital Perirectal Dermoid Cyst: A Rare Cause of Complex, Recurrent Pediatric Fistula-in-ano

open access: yesFrontiers in Pediatrics, 2018
Perianal abscess and fistula-in-ano are well-described in the pediatric population. They are most common in infants less than 1 year of age and often resolve with oral antibiotics; occasionally they require drainage or fistulotomy.
Wesley E. Barry   +9 more
doaj   +1 more source

Ligation of intersphincteric fistula tract for complex fistula in ano at a tertiary care centre in Northern India: A 3-year prospective study

open access: yesJournal of Clinical Sciences
Background: An anal fistula is an abnormal pathological tract between the anal canal and the perianal skin which primarily originates from the crypto-glandular infection.
Musharraf Husain   +3 more
doaj   +1 more source

Effectiveness and Safety of Advanced Dual‐Targeted Therapy in Refractory Perianal Crohn's Disease

open access: yesUnited European Gastroenterology Journal, Volume 13, Issue 8, Page 1491-1501, October 2025.
ABSTRACT Introduction Perianal Crohn's disease (CD) remains challenging to treat despite the increasing number of advanced therapies. Advanced dual‐targeted therapy has emerged as a new treatment option in CD, but no data are available for perianal CD. The aim of this study was to evaluate the effectiveness and safety of advanced dual‐targeted therapy ...
Nadia Fathallah   +9 more
wiley   +1 more source

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