Results 51 to 60 of about 4,241 (177)
Perioperative utilization of JAK inhibitors in Perianal Fistulizing Crohn's disease
Abstract With the recent approval of small molecule drugs such as upadacitinib in adult inflammatory bowel disease (IBD), their utilization is becoming more common; however, there is limited data on perioperative risks or optimal timing of cessation and resumption to mitigate flares. Current recommendations suggest holding these medications for 14 days
Alexander Lyons +2 more
wiley +1 more source
Diagnosis and Management of a Cryptoglandular Actinomycotic Fistula-in-Ano: An Update on 7 New Cases and a Review of the Literature [PDF]
Purpose Primary anal actinomycosis of cryptoglandular origin, a rare cause of anal suppurative disease, requires specific management to be cured. The aims of this retrospective study were to describe clinical, morphological, and microbiological features ...
Axel Egal +6 more
doaj +1 more source
Recurrence of disease after surgery for fistula occurs in approximately 30%–40% of patients. Treatment of a recurrent fistula has an increased risk of failure and further recurrence.
Vaishnavi Gunasekharan +5 more
doaj +1 more source
Isolated anal tuberculosis presenting as an anal fistula in an immunocompetent child
Abstract Extra‐pulmonary tuberculosis accounts for less than 15% of all tuberculosis cases, while intestinal tuberculosis accounts for less than 1% of extra‐pulmonary forms of the disease. Abdominal organ involvement is more common, but extension to the ano‐perineal region is extremely rare.
Mariam Lagrine +4 more
wiley +1 more source
Autologous Adipose Tissue Injection as Treatment for Ileoanal Pouch‐Related Fistulae
ABSTRACT Background Ileal pouch‐anal anastomosis (IPAA) is a standard surgical procedure for ulcerative colitis (UC) and familial adenomatous polyposis. However, pouch‐related fistulae (PRF) are a significant complication. There is no consensus on the optimal treatment for PRF.
Hayder Alqaisi +3 more
wiley +1 more source
Background Traditional Indian medicine has been used to treat a variety of illnesses for centuries. However, there are existing concerns surrounding its heavy metal content. Amongst the different systems of traditional Indian medicine, Ayurvedic medicine has been most frequently implicated in heavy metal toxicity, while Siddha medicine has only very ...
Zhibin Tan +8 more
wiley +1 more source
Tea and Blood–Brain Barrier Homeostasis: Potential Mechanisms and Improvement Strategies
Abstract The blood–brain barrier (BBB), a selective interface regulating cerebral substance exchange, plays a crucial role in maintaining cognitive function and metabolic balance. While tea consumption has been traditionally associated with health benefits, its specific effects on BBB integrity warrant systematic investigation. This review demonstrates
Rongbosen Yue +5 more
wiley +1 more source
Congenital Perirectal Dermoid Cyst: A Rare Cause of Complex, Recurrent Pediatric Fistula-in-ano
Perianal abscess and fistula-in-ano are well-described in the pediatric population. They are most common in infants less than 1 year of age and often resolve with oral antibiotics; occasionally they require drainage or fistulotomy.
Wesley E. Barry +9 more
doaj +1 more source
Background: An anal fistula is an abnormal pathological tract between the anal canal and the perianal skin which primarily originates from the crypto-glandular infection.
Musharraf Husain +3 more
doaj +1 more source
Effectiveness and Safety of Advanced Dual‐Targeted Therapy in Refractory Perianal Crohn's Disease
ABSTRACT Introduction Perianal Crohn's disease (CD) remains challenging to treat despite the increasing number of advanced therapies. Advanced dual‐targeted therapy has emerged as a new treatment option in CD, but no data are available for perianal CD. The aim of this study was to evaluate the effectiveness and safety of advanced dual‐targeted therapy ...
Nadia Fathallah +9 more
wiley +1 more source

