Results 61 to 70 of about 2,707,259 (240)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Water in the 2003 Virginia General Assembly

open access: yes, 2003
The 2003 Virginia General Assembly convened on January 8 and adjourned on February 22, with a reconvened (“veto”) session on April 2. The legislature considered 3277 measures; 1585 passed and 1692 failed. The legislature also considered amendments to the
Virginia Water Resources Research Center
core  

Application of CCME WQI to evaluate feasibility of potable water availability: A case study of Tehri dam reservoir

open access: yesEnvironment Conservation Journal, 2014
In the present research work, the Canadian Council of Ministers of the Environment water quality index 1.0 (CCME WQI 1.0) was applied to assess water quality of Tehri dam reservoir by using the drinking water standard prescribed by the WHO (1999) and BIS
R. Bhutiani   +3 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Water in the 2000 Virginia General Assembly

open access: yes, 2000
The Virginia General Assembly held its 2000 session from January 12 to March 10. Lawmakers considered 3,172 bills and resolutions (compared to 2,735 measures considered in 1999).
Virginia Water Resources Research Center
core  

Evaluation of groundwater quality and its suitability for drinking and irrigation using GIS and geostatistics techniques in semiarid region of Neyshabur, Iran

open access: yesApplied Water Science, 2018
Groundwater is a vital source for drinking and agricultural purposes in semiarid region of Neyshabur area (Iran). The present study assessed the groundwater quality and mapped the spatial variation of water samples in terms of suitability for drinking ...
Gouri Sankar Bhunia   +4 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Research in water resources for Idaho

open access: yes, 1963
Summary of the goals, priorities and mission of the University of Idaho's Policy and Coordinating Committee on Water Resources and the Water Resources Committee. Summary of ongoing research. Lists priority of needs for future work.
University of Idaho, Water Resources Committee
core  

The Arabana people, water and developing cultural indicators for country [PDF]

open access: yes, 2015
Water is of paramount importance to the Arabana people who live in the Kati Thanda-Lake Eyre region. Assessing the ongoing condition of aquatic ecosystems is an important part of management.
Nursey-Bray, M.J.   +1 more
core  

Flood forecasting using a coupled hydrological and hydraulic model (based on FVM) and highresolution meteorological model

open access: yesE3S Web of Conferences, 2018
A forecasting systems based on the coupling of meteorological, hydrologic, hydraulic and risk models is used to minimize the risks associated to water scarcity and flooding.
Sanz-Ramos Marcos   +4 more
doaj   +1 more source

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