Results 111 to 120 of about 82,231,178 (266)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Symposium: Ravishing: The Rose in Fashion: Rose Motifs in the Collection of The Museum at FIT

open access: yes
Colleen Hill and Elizabeth Way present "Rose Motifs in the Collection of The Museum at FIT" for The Museum at FIT's 24th academic symposium Ravishing: The Rose in Fashion on April 30, 2021.

core  

Is the 10 g monofilament fit for purpose for diagnosing DPN?

open access: yesBMJ Open Diabetes Research & Care, 2023
Rayaz A Malik
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Are current systems of global health academia fit for purpose?

open access: yesThe Lancet Global Health, 2021
Keerti Gedela
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

FIT Oral History: John Pomerantz (Part 2)

open access: yes
DATE INTERVIEWED: circa 1980sSUMMARY: Mildred Finger interviews John Pomerantz of Leslie Fay, Inc.BIOGRAPHY: "John J. Pomerantz, president of JJP Advisory, LLC, is former chairman and chief executive officer of Leslie Fay Company, Inc., a manufacturer of

core  

Microbiological hazards associated with the use of water in the post‐harvest handling and processing operations of fresh and frozen fruits, vegetables and herbs (ffFVH). Part 3 (Fresh‐whole FVH process water management plan)

open access: yesEFSA Journal
Water used in post‐harvest handling and processing operations is an important risk factor for microbiological cross‐contamination of fruits, vegetables and herbs (FVH).
EFSA BIOHAZ Panel (EFSA Panel on Biological Hazards)   +22 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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