Results 111 to 120 of about 82,231,178 (266)
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Symposium: Ravishing: The Rose in Fashion: Rose Motifs in the Collection of The Museum at FIT
Colleen Hill and Elizabeth Way present "Rose Motifs in the Collection of The Museum at FIT" for The Museum at FIT's 24th academic symposium Ravishing: The Rose in Fashion on April 30, 2021.
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Is the 10 g monofilament fit for purpose for diagnosing DPN?
Rayaz A Malik
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Are current systems of global health academia fit for purpose?
Keerti Gedela
doaj +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
FIT Oral History: John Pomerantz (Part 2)
DATE INTERVIEWED: circa 1980sSUMMARY: Mildred Finger interviews John Pomerantz of Leslie Fay, Inc.BIOGRAPHY: "John J. Pomerantz, president of JJP Advisory, LLC, is former chairman and chief executive officer of Leslie Fay Company, Inc., a manufacturer of
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Water used in post‐harvest handling and processing operations is an important risk factor for microbiological cross‐contamination of fruits, vegetables and herbs (FVH).
EFSA BIOHAZ Panel (EFSA Panel on Biological Hazards) +22 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source

