Results 111 to 120 of about 471,546 (242)

Are the Australian Dietary Guidelines Fit for Purpose for Culturally Diverse Populations? A Qualitative Study. [PDF]

Health Promot J Austr
Narsh H, Gallegos D.
europepmc   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Editorial: Complaints mechanisms in research: are they fit for purpose?

Research Ethics Review, 2022
Kate Chatfield
doaj   +1 more source

Exploration of the clinical exercise physiologist standards in the UK: are they fit for purpose and how could they be developed? [PDF]

BMJ Open Sport Exerc Med
Crozier A, Osin C, Sadler I, Graves LEF, Rycroft J, Dawson E, Miller G, Green DJ, Naylor L, Askew CD, Jones H.   +10 more
europepmc   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Fit for purpose: German contributions to the new ICRP recommendations. [PDF]

Radiat Environ Biophys
Birschwilks M, Azimzadeh O, Scholz-Kreisel P, Eidemüller M, Moertl S, Breustedt B, Li WB, Gruß M, Werner C, Steiner M, Gerstmann U, Woda C, Vogt J, Gering F, Winter KS, Mille EB, Giussani A, Akbarian GS, Pölzl-Viol C.   +18 more
europepmc   +1 more source

Fit for purpose [PDF]

Nature, 2014
openaire   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Assessing the Carcinogenic Potential of Jet Fuels: A Fit-for-Purpose Systematic Literature Review. [PDF]

J Occup Environ Med
Heitz ER, Allen BD, Goodman SJ, Freedman AN, Miller SL, Snow SJ, Eftim SE, Haver CE, Weinberger KR, Bergeron JG, Vincent-Hall TD.   +10 more
europepmc   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source