Results 121 to 130 of about 59,495,041 (290)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Symposium: Ravishing: The Rose in Fashion: Rose Motifs in the Collection of The Museum at FIT
Colleen Hill and Elizabeth Way present "Rose Motifs in the Collection of The Museum at FIT" for The Museum at FIT's 24th academic symposium Ravishing: The Rose in Fashion on April 30, 2021.
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Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
FIT Oral History: John Pomerantz (Part 2)
DATE INTERVIEWED: circa 1980sSUMMARY: Mildred Finger interviews John Pomerantz of Leslie Fay, Inc.BIOGRAPHY: "John J. Pomerantz, president of JJP Advisory, LLC, is former chairman and chief executive officer of Leslie Fay Company, Inc., a manufacturer of
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Purpose Driven Partnerships: The Nexus of Purpose and Strategic Alliances
This dissertation utilizes an abductive mixed methods study to assess, unpack, and extend the theory of purpose. Although prior literature primarily focuses on the outcomes of high purpose framing, this study specifically addresses how one high-purpose ...
Bailey, Ryan
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Inequality, unemployment and precarity [PDF]
The COVID-19 pandemic is causing an economic crisis that the world has not witnessed since the Great Depression of the 1930s. The projected loss of jobs is expected to be at least 230 million worldwide in the second quarter of this year.
Institute for Innovation and Public Purpose
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
FIT Oral History: John Pomerantz (Part 1)
DATE INTERVIEWED: November 11, 1981 & March 3, 1982SUMMARY: Mildred Finger interviews John Pomerantz of Leslie Fay, Inc.Mildred Finger interviewed John Pomerantz again at a later date, possibly also in 1982.
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