Results 121 to 130 of about 5,260,239 (232)
Promotion as contrastive increase in expected fit [PDF]
, 2019 What is required for an action to promote the satisfaction of a desire? We reject extant answers and propose an alternative. Our account differs from competing answers in two ways: first, it is contrastive, in that actions promote the satisfaction of ...
Dellsén, Finnur, Sharadin, Nathaniel
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Penilaian Kejayaan Pelaksanaan Sistem Pengurusan Maklumat Pendidikan (EMIS) di Sekolah
Journal of ICT in Education, 2019 Kajian ini bertujuan untuk menilai kejayaan pelaksanaan sistem maklumat dalam sektor pendidikan di Malaysia khususnya Sistem Pengurusan Maklumat Pendidikan (EMIS).
Razana Baharudin, Noriza Nayan
doaj
Trembling motion of electrons driven by Larmor spin precession
npj SpintronicsWe show that the initialization of an ensemble of electrons in the same spin state in strained n-InGaAs subject to a perpendicular magnetic field triggers an AC electric current at GHz frequencies.
Ivan Stepanov +6 more
doaj +1 more source
The Journal of Indian Prosthodontic SocietyAims: The objectives of the study were to compare the adaptation of presintered zirconia and cobalt– chromium prostheses using microcomputed tomography (μCT), scanning electron microscopy (SEM), and stereomicroscope (SM).
Elie E. Daou, Pascale Salameh
doaj +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source