Results 131 to 140 of about 2,524,804 (317)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Designer Spotlight: Charles James

open access: yes
The Museum at FIT presents its Designer Spotlight series where MFIT curators explore objects in our permanent collection that highlight a specific designer's work and their contributions to fashion.Charles James was a designer’s designer.

core  

Aproximación a la obra periodí­stica de Tomás Eloy Martí­nez: representaciones de lo nacional e imágenes de escritor

open access: yesOrbis Tertius, 2014
El presente trabajo aborda la obra periodí­stica de Tomás Eloy Martí­nez publicada en sus últimas antologí­as. En el análisis, se priorizan los modos en que su escritura frecuenta los géneros hí­bridos, la construcción de la imagen de escritor que emerge
Rocío Celeste Fit
doaj  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

FIT Soul Fashion Show: 1983 part 1

open access: yes
The FIT Soul Club presents the 1983 Soul Fashion Show. Featuring work by student designers Berton Ridley, Brenda Evans, Leyland Michael, Laurie Barr, David Signley, Adrienne Jones, Brian Lane, Marva Patterson, Brian Lynch, Dhondi Burrell, David Emmett ...

core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

FIT Soul Fashion Show: 1983 part 2

open access: yes
The FIT Soul Club presents the 1983 Soul Fashion Show. Featuring work by student designers and alumni Roger Hinds, Jurvis Jarvis, Cheryl Williams, Keith Martin and Alexander Young as Young Martin, Ron Chew, Cheryl McKenzie, Sherri Hobson, Steve Cutting ...

core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

FIT Soul Fashion Show: 1983 part 3

open access: yes
The FIT Soul Club presents the 1983 Soul Fashion Show. Featuring work by student designers and alumni and a salute to club advisor, Clara Branch.

core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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