Results 151 to 160 of about 2,524,804 (317)
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Risk-adapted intervals for colorectal cancer screening using fecal immunochemical tests: a modelling study based on the BLITZ cohort. [PDF]
BMC MedHeisser T +3 more
europepmc +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
FIT Talks: Albert Kresch Interview
Albert Kresch was a professor at the Fashion Institute of Technology (FIT) from 1951 to 1986, one of the longest professorial tenures in FIT's history. Born in Scranton, Pennsylvania, the Great Depression forced his family to move to New York when he was
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Effects of restorative material, intraoral scanner, and digital workflow on the marginal and internal fit of CAD-CAM all-ceramic crowns: an <i>in vitro</i> study. [PDF]
J Adv ProsthodontMusa J +5 more
europepmc +1 more source
Remaining Fit: On the Creation and Maintenance of Fit.
, 2004 This paper serves as the introductory note to the Fifth Workshop on Business Process Modeling, Development, and Support (BPMDS’04). The workshop focuses on the exploration of issues related to the fit between business processes and Business Process Support (BPS) systems.
Regev, Gil, Wegmann, Alain
openaire +2 more sources
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
FIT Talks: Camille Block Interview
Camille Block interviewed by Karen Trivette.Camille Block lectures on Intimate Apparel and Swimwear design for the Center for Continuing and Professional Studies at the Fashion Institute of Technology.
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