Results 141 to 150 of about 49,034 (303)
Mutational fitness landscape and drug resistance. [PDF]
Curr Opin Struct Biol, 2023 Flynn J +4 more
europepmc +1 more source
Photothermal‐Activated Antibacterial Amyloid‐Polyphenol‐Iron Hydrogels for Synergistic Wound Healing
Advanced Healthcare Materials, EarlyView.We report a thermally triggered supramolecular hydrogel (LTFe) formed by Fe3+ and tannic acid on lysozyme amyloid fibrils. Fe3+ enables rapid gelation and photothermal transduction with an efficiency of 88.56%. The LTFe hydrogel exhibits excellent biocompatibility, potent antibacterial activity against E. coli and S.
Di Wu +8 more
wiley +1 more source
Advantage of recombination on a smooth fitness landscape.
, 2014 The figure shows time series of (A) mean fitness and (B) difference of the mean fitnesses for recombining () and non-recombining () populations in an additive landscape. Time is measured in discrete generations.
Stefan Nowak (631482) +3 more
core +1 more source
Advanced Healthcare Materials, EarlyView.We develop a covalent organic framework‐loaded Traditional Chinese Medicine monomer nanodrug delivery system (ISL@bCOF) via boron‐oxygen bonds, a smart response to glucose for delivering AI‐driven isoliquiritigenin (ISL) targeting ZBP1. This dynamic release mechanism, combined with transdermal delivery technology via potent microneedles, can modulate ...
Menghan Zhou +9 more
wiley +1 more source
Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application
Advanced Materials, EarlyView.This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong +12 more
wiley +1 more source
Microbial BiotechnologyBeyond the rational construction of genetic determinants to encode target functions, complex phenotype engineering requires the contextualisation of their expression within the metabolic and genetic background of the host strain.
Blas Blázquez, Juan Nogales
doaj +1 more source
Advanced Materials, EarlyView.AI‐Assisted Workflow for (Scanning) Transmission Electron Microscopy: From Data Analysis Automation to Materials Knowledge Unveiling. Abstract (Scanning) transmission electron microscopy ((S)TEM) has significantly advanced materials science but faces challenges in correlating precise atomic structure information with the functional properties of ...
Marc Botifoll +19 more
wiley +1 more source
Fitness Landscape Analysis of Feed-Forward Neural Networks [PDF]
, 2019 Thesis (PhD)--University of Pretoria, 2019.Neural network training is a highly non-convex optimisation problem with poorly understood properties. Due to the inherent high dimensionality, neural network search spaces cannot be intuitively visualised, thus
core
Environmental modulation of global epistasis in a drug resistance fitness landscape. [PDF]
Nat Commun, 2023 Diaz-Colunga J +2 more
europepmc +1 more source