Results 61 to 70 of about 172,900 (260)
Fractional calculus model of electrical impedance applied to human skin. [PDF]
PLoS ONE, 2013 Fractional calculus is a mathematical approach dealing with derivatives and integrals of arbitrary and complex orders. Therefore, it adds a new dimension to understand and describe basic nature and behavior of complex systems in an improved way.
Zoran B Vosika +3 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Tidskrift för Litteraturvetenskap, 2012 Fitting in and Rebelling: On the Ambivalence towards Tradition in Modern Swedish Working-Class Literature This article analyzes the ambivalent attitude of several Swedish working-class writers towards the tradition of working-class literature during ...
Magnus Nilsson
doaj +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Local Fitting sets and the injectors of a finite group
Журнал Белорусского государственного университета: Математика, информатика, 2019 The product F ◊ X of the Fitting set F of a group G and the Fitting class X is called the set of subgroups {H ≤ G: H/HF ∈ X}. Let P be the set of all primes, ∅ ≠ π ⊆ P, π′ = P\π and Eπ′ denote the class of all π′-groups.
Tatyana B. Karaulova
doaj
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Illuminating Youth: Decades of Mid-infrared Variability and Color Evolution of Young Stellar Objects
The Astrophysical Journal Supplement SeriesThe variability of young stellar objects (YSOs) is a crucial tool for understanding the mechanisms driving flux changes. In this study, we present an infrared variability analysis of a large sample of over 20,000 candidate YSOs, using data from the ...
Sharma Neha, Saurabh Sharma
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Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source