Results 51 to 60 of about 491,546 (266)

The CogniAid trial. The impact of two hearing aid signal processing strategies on cognition

open access: yesFrontiers in Audiology and Otology
BackgroundUntreated hearing loss is a risk factor for age-related cognitive decline and hearing aids have been shown to slow cognitive decline in a population at risk for dementia.
Grant Donald Searchfield   +17 more
doaj   +1 more source

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa   +3 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Local Fitting sets and the injectors of a finite group

open access: yesЖурнал Белорусского государственного университета: Математика, информатика, 2019
The product F  ◊  X of the Fitting set F of a group G and the Fitting class X is called the set of subgroups {H ≤ G: H/HF ∈ X}. Let P be the set of all primes, ∅ ≠ π ⊆ P, π′ = P\π and Eπ′ denote the class of all π′-groups.
Tatyana B. Karaulova
doaj  

Fitting like subgroups of finite groups

open access: yes, 2021
In this paper the concept of $\mathbb{F}$-functorial of a finite group was introduced. These functorials have many properties of the Fitting subgroup of a soluble group and the generalized Fitting subgroup of a finite group. It was shown that the set of all $\mathbb{F}$-functorials is a complete distributive lattice and the cardinality of this lattice ...
Murashka, Viachaslau I.   +1 more
openaire   +2 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Influences of alpine meadow degradation on species diversity and abundance distribution of plant functional groups in Gannan

open access: yesXibei zhiwu xuebao
[Objective] To investigate the response of species diversity and richness distribution of plant functional groups to degradation in the Gannan alpine meadow, we analyzed the community construction mechanism and resource utilization of different plant ...
LIU Minxia, LIU Cheng , YANG Chunliang
doaj   +1 more source

\(\Omega\)-foliated Fitting classes of \(T\)-groups

open access: yesSibirskie Elektronnye Matematicheskie Izvestiya, 2017
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Bazhanova, E. N., Vedernikov, V. A.
openaire   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

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