Results 51 to 60 of about 314,896 (305)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Development of a Novel MultiBody Mechatronic Model for Five-Axis CNC Machine Tool [PDF]

, 2015
The paper presents the development of a mechatronic hybrid model for Geiss five-axis CNC machine tool using MultiBody-System (MBS) approach. The motion control systems comprising electrical and mechanical elements are analyzed and modeled.
Papananias, M., Pislaru, Crinela, Sztendel, S.   +2 more
core  

A methodology for the lightweight design of modern transfer machine tools [PDF]

, 2018
This paper deals with a modern design approach via finite elements in the definition of the main structural elements (rotary table and working unit) of an innovative family of transfer machine tools. Using the concepts of green design and manufacture, as
Cavalli, Omar, Croccolo, Dario, De Agostinis, Massimiliano, Fini, Stefano, Olmi, Giorgio, Robusto, Francesco, Vincenzi, Nicol\uf2   +6 more
core   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Motion and Virtual Cutting Simulation System for a Five-Axis Virtual Machine Tool

International Journal of Automation and Smart Technology, 2011
Since five-axis machine tools are very costly and their use requires a high level of knowledge and expertise, a virtual machine tool must be used to simulate five-axis machine tool operation. Configuration code or a mechanism topology matrix must be used
Rong-Shean Lee, Ko-Jen Mei
doaj   +1 more source

Optical equipment for measuring deformation of machine tool components [PDF]

, 2016
This paper describes the possibilities of measuring deformation of machine tool components based on monitoring change in the optical beam path. Deformation is evaluated relatively between an optical beam source and a sensing element.
Chládek Š., Diviš I., Koubek J., Švéda J.   +3 more
core   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Analysis of kinematic motion deviations of machining centers based on geometric tolerances

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2014
The objectives of the present research are to investigate relationships between kinematic motion deviations of machine tools and geometric tolerances of their components, to propose mathematical models representing kinematic motion deviations of five ...
Atsushi TAKAHASHI, Arata YOSHIDA, Wiroj THASANA, Nobuhiro SUGIMURA, Koji IWAMURA, Yoshitaka TANIMIZU   +5 more
doaj   +1 more source

Experimental Investigation of the Effects of Machining Parameters on the Performance of Form-Cutting Tools Manufactured by Wire Electrical Discharge Machining (WEDM) and Grinding Processes

Micromachines, 2023
In this research, a comparison between two methods of grinding and WEDM and the chip formation of each form tool was studied through a set of designs of experiments.
Amir Alinaghizadeh, Mohammadjafar Hadad, Bahman Azarhoushang   +2 more
doaj   +1 more source

Error Modeling and Sensitivity Analysis of a Five‐Axis Machine Tool [PDF]

Mathematical Problems in Engineering, 2014
Geometric error modeling and its sensitivity analysis are carried out in this paper, which is helpful for precision design of machine tools. Screw theory and rigid body kinematics are used to establish the error model of an RRTTT‐type five‐axis machine tool, which enables the source errors affecting the compensable and uncompensable pose accuracy of ...
Wenjie Tian, Weiguo Gao, Wenfen Chang, Yingxin Nie   +3 more
openaire   +1 more source