Results 61 to 70 of about 314,896 (305)

Multi-agent framework based on smart sensors/actuators for machine tools control and monitoring [PDF]

, 2006
Throughout the history, the evolutions of the requirements for manufacturing equipments have depended on the changes in the customers' demands. Among the present trends in the requirements for new manufacturing equipments, there are more flexible and ...
Archimède, Bernard, Desforges, Xavier
core   +3 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Comparison of Volumetric Analysis Methods for Machine Tools with Rotary Axes [PDF]

, 2009
Confidence in the ability of a production machine to meet manufacturing tolerances requires a full understanding of the accuracy of the machine. However, the definition of “the accuracy of the machine” is open to interpretation. Historically, this has
Fletcher, Simon, Longstaff, Andrew P., Myers, Alan, Poxton, Anthony   +3 more
core  

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Machining strategy development in 5-axis milling operations using process models [PDF]

, 2010
Increased productivity and part quality can be achieved by selecting machining strategies and conditions properly. At one extreme very high speed and feed rate with small depth of cut can be used for high productivity whereas deep cuts accompanied with ...
Budak, Erhan, Murtezaoglu, Yavuz, Murtezaoğlu, Yavuz, Ozkirimli, Omer Mehmet, Ozturk, Erdem, Tunc, Taner L., Tunç, Taner L., Özkırımlı, Ömer Mehmet, Öztürk, Erdem   +8 more
core  

Evaluation of servo, geometric and dynamic error sources on five axis high-speed machine tool

, 2011
Many sources of errors exist in the manufacturing process of complex shapes. Some approximations occur at each step from the design geometry to the machined part.
Andolfatto, Loïc, Lavernhe, Sylvain, Mayer, René   +2 more
core   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

A Method to Optimize Geometric Errors of Machine Tool based on SNR Quality Loss Function and Correlation Analysis

MATEC Web of Conferences, 2017
Instead improving the accuracy of machine tool by increasing the precision of key components level blindly in the production process, the method of combination of SNR quality loss function and machine tool geometric error correlation analysis to optimize
Cai Ligang, Li Jiaying, Cheng Qiang, Sun Bingwei, Wang Yan   +4 more
doaj   +1 more source

Pick-interval scallop heightestimation using three types of geometrical end mill cutters on CNC milling machine [PDF]

Engineering and Technology Journal, 2013
This research presents the theoretical model, simulation and experimental verification to predict the magnitude of scallop height using 3 and 5-axis milling machine, where the effect of geometrical shape of the workpiece relative to the effect of ...
Ahmed A.A.Duroobi, Jamal Mohamed, Bahha I. Kazem, Chen Wenlaing   +3 more
doaj   +1 more source

Design, implementation, and testing of advanced virtual coordinate-measuring machines [PDF]

, 2012
Copyright @ 2011 IEEE. This article has been made available through the Brunel Open Access Publishing Fund.Advanced virtual coordinate-measuring machines (CMMs) (AVCMMs) have recently been developed at Brunel University, which provide vivid graphical ...
Hu, Y, Sun, X, Yang, Q
core   +1 more source