Results 91 to 100 of about 169,165 (309)

A Novel Method for the Fault Diagnosis of a Planetary Gearbox based on Residual Sidebands from Modulation Signal Bispectrum Analysis [PDF]

, 2014
This paper presents a novel method for the fault diagnosis of planetary gearboxes based on an accurate estimation of residual sidebands using a modulation signal bispectrum (MSB).
Abdalla, Gaballa M., Ball, Andrew, Gu, Fengshou, Xun, Haijun, Zhang, Riliang   +4 more
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Solar array fed synchronous reluctance motor driven water pump : an improved performance under partial shading conditions [PDF]

, 2019
An improved performance of a photovoltaic (PV) pumping system employing a synchronous reluctance motor (SynRM) under partial shading conditions is proposed.
Al-Dhaifallah, Mujahed, Ibrahim, Mohamed Nabil Fathy, Rezk, Hegazy, Sergeant, Peter   +3 more
core   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Neural Network-Based Model Reference Adaptive System for Torque Ripple Reduction in Sensorless Poly Phase Induction Motor Drive

Energies, 2019
This paper proposes the modified, extended Kalman filter, neural network-based model reference adaptive system and the modified observer technique to estimate the speed of a five-phase induction motor for sensorless drive.
S. Usha, C. Subramani, Sanjeevikumar Padmanaban   +2 more
doaj   +1 more source

Basic Comparison and Evaluation of Functionality AC-AC Matrix Converter Concepts for HEV Vehicle - Part II

Communications, 2020
The paper deals with a modeling and simulation of the direct AC-AC propulsion system and compares two matrix converter concepts with five-phase traction induction motors (IM) for the hybrid electric vehicle (HEV).
Branislav Dobrucky, Slavomir Kascak, Michal Prazenica, Roman Konarik   +3 more
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Dual-parameter identification based on model reference adaptive system for five-phase induction motor

电力工程技术
The five-phase induction motor, known for its simplicity among multiphase induction motors, offers benefits such as low noise, minimal torque ripple, and high load capacity, rendering it suitable for applications demanding high power and reliability.
Xinguo HOU, Xiangyu LUO, Xuan TU
doaj   +1 more source