DNA Sequence Variants in the Five Prime Untranslated Region of the Cyclooxygenase-2 Gene Are Commonly Found in Healthy Dogs and Gray Wolves. [PDF]
The aim of this study was to investigate the frequency of regional DNA variants upstream to the translation initiation site of the canine Cyclooxygenase-2 (Cox-2) gene in healthy dogs.
Noa Safra+7 more
doaj +8 more sources
Correction: DNA Sequence Variants in the Five Prime Untranslated Region of the Cyclooxygenase-2 Gene Are Commonly Found in Healthy Dogs and Gray Wolves. [PDF]
[This corrects the article DOI: 10.1371/journal.pone.0133127.].
Noa Safra+7 more
doaj +7 more sources
Association of a bovine prion gene haplotype with atypical BSE. [PDF]
BACKGROUND: Atypical bovine spongiform encephalopathies (BSEs) are recently recognized prion diseases of cattle. Atypical BSEs are rare; approximately 30 cases have been identified worldwide. We tested prion gene (PRNP) haplotypes for an association with
Michael L Clawson+7 more
doaj +1 more source
dbCNV: deleteriousness-based model to predict pathogenicity of copy number variations
Background Copy number variation (CNV) is a type of structural variation, which is a gain or loss event with abnormal changes in copy number. Methods to predict the pathogenicity of CNVs are required to realize the relationship between these variants and
Kangqi Lv+6 more
doaj +1 more source
$\ge 4 μ$ signal from a vector-like lepton decaying to a muon-philic $Z^\prime$ boson at the LHC [PDF]
We propose a novel possibility to detect a very distinctive signal with more than four muons originating from pair-produced vector-like leptons decaying to a muon-philic $Z^\prime$ boson. These new particles are good candidates to explain the anomalies in the muon anomalous magnetic moment and the $b\to s\ell\ell$ processes.
arxiv +1 more source
Glutathione peroxidase 1 (cellular glutathione peroxidase, EC 1.11.1.9 (GPX1)) is an antioxidant enzyme that plays an important role in scavenging reactive oxygen species to protect cells from oxidative damage.
Sopon Wilaison, Makoto Mori
doaj +1 more source
Improved annotation of 3-prime untranslated regions and complex loci by combination of strand-specific Direct RNA Sequencing, RNA-seq and ESTs [PDF]
The reference annotations made for a genome sequence provide the framework for all subsequent analyses of the genome. Correct annotation is particularly important when interpreting the results of RNA-seq experiments where short sequence reads are mapped against the genome and assigned to genes according to the annotation. Inconsistencies in annotations
arxiv +1 more source
DT-grams: Structured Dependency Grammar Stylometry for Cross-Language Authorship Attribution [PDF]
Cross-language authorship attribution problems rely on either translation to enable the use of single-language features, or language-independent feature extraction methods. Until recently, the lack of datasets for this problem hindered the development of the latter, and single-language solutions were performed on machine-translated corpora.
arxiv
A genomic map of the effects of linked selection in Drosophila [PDF]
Natural selection at one site shapes patterns of genetic variation at linked sites. Quantifying the effects of 'linked selection' on levels of genetic diversity is key to making reliable inference about demography, building a null model in scans for targets of adaptation, and learning about the dynamics of natural selection.
arxiv +1 more source
A 5' UTR Language Model for Decoding Untranslated Regions of mRNA and Function Predictions [PDF]
The 5' UTR, a regulatory region at the beginning of an mRNA molecule, plays a crucial role in regulating the translation process and impacts the protein expression level. Language models have showcased their effectiveness in decoding the functions of protein and genome sequences. Here, we introduced a language model for 5' UTR, which we refer to as the
arxiv