Results 91 to 100 of about 22,958 (200)

Preferential superficial cortical layer activation during seizure propagation

open access: yesEpilepsia, Volume 66, Issue 3, Page 929-941, March 2025.
Abstract Objective Focal cortical seizures travel long distances from the onset zone, but the long‐distance propagation pathways are uncertain. In vitro and in vivo imaging techniques have investigated the local spread of seizures but did not elucidate long‐distance spread. Furthermore, classical studies in slices suggested seizure spread locally along
Anastasia Brodovskaya   +4 more
wiley   +1 more source

Unraveling the functional dynamics of Caenorhabditis elegans stress‐responsive omega class GST‐44

open access: yesThe FEBS Journal, EarlyView.
Omega‐class glutathione S‐transferases (GSTs) are integral to redox regulation and cellular stress responses. This study characterized GST‐44 in Caenorhabditis elegans, revealing its predominant expression in the intestine and excretory H‐cell, with significant upregulation under various stress conditions.
Charlotte Sophia Kaiser   +9 more
wiley   +1 more source

Evidence that genetic drift not adaptation drives fast‐Z and large‐Z effects in Ficedula flycatchers

open access: yesMolecular Ecology, EarlyView.
Abstract The sex chromosomes have been hypothesized to play a key role in driving adaptation and speciation across many taxa. The reason for this is thought to be the hemizygosity of the heteromorphic part of sex chromosomes in the heterogametic sex, which exposes recessive mutations to natural and sexual selection. The exposure of recessive beneficial
Madeline A. Chase   +2 more
wiley   +1 more source

The Evolution of Locally Adaptive Chromosome Inversions in Mimulus guttatus

open access: yesMolecular Ecology, EarlyView.
ABSTRACT Chromosomal inversion polymorphisms are ubiquitous across the diversity of diploid organisms and play a significant role in the evolution of adaptations in those species. Inversions are thought to operate as supergenes by trapping adaptive alleles at multiple linked loci through the suppression of recombination. While there is now considerable
Leslie M. Kollar   +4 more
wiley   +1 more source

Molecular changes in agroinfiltrated leaves of Nicotiana benthamiana expressing suppressor of silencing P19 and coronavirus‐like particles

open access: yesPlant Biotechnology Journal, EarlyView.
Summary The production of coronavirus disease 2019 vaccines can be achieved by transient expression of the spike (S) protein of severe acute respiratory syndrome coronavirus 2 in agroinfiltrated leaves of Nicotiana benthamiana. Relying on bacterial vector Agrobacterium tumefaciens, this process is favoured by co‐expression of viral silencing suppressor
Louis‐Philippe Hamel   +9 more
wiley   +1 more source

A chaperonin BnaC01.CCT8 contributes to silique length and seed weight by affecting auxin and jasmonic acid signalling in Brassica napus

open access: yesPlant Biotechnology Journal, EarlyView.
Summary Seed weight (SW), which is directly influenced by silique length (SL), is a critical agronomic trait significantly affecting both the quality and yield of rapeseed. In this study, a shorter silique length (ssl) mutant was generated through ethyl methane sulfonate mutagenesis, exhibiting reduced SL and SW compared to the wild type.
Zhaoyang Qu   +11 more
wiley   +1 more source

Largest genome assembly in Brassicaceae: retrotransposon‐driven genome expansion and karyotype evolution in Matthiola incana

open access: yesPlant Biotechnology Journal, EarlyView.
Summary Matthiola incana, commonly known as stock and gillyflower, is a widely grown ornamental plant whose genome is significantly larger than that of other species in the mustard family. However, the evolutionary history behind such a large genome (~2 Gb) is still unknown.
Daozong Chen   +14 more
wiley   +1 more source

Identification of a hydroxycinnamoyl‐CoA double bond reductase (HDR) affirms multiple pathways for dihydrochalcone formation in apple

open access: yesPlant Biotechnology Journal, EarlyView.
Summary Dihydrochalcones are secondary metabolites with manifold dietary and pharmaceutical properties, but with a yet unclear function in plants. The abundance of dihydrochalcones, particularly phloridzin, makes Malus ssp. unique in the plant kingdom. The gene(s)/enzyme(s) for the key reaction in phloridzin biosynthesis, the reduction in the C3‐bridge
Susan Schröpfer   +14 more
wiley   +1 more source

The 14‐3‐3 Protein SlTFT1 Accelerates Tomato Fruit Ripening by Binding and Stabilising YFT1 in the Ethylene Signalling Pathway

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Ethylene plays a pivotal role during the fruit ripening process in tomato (Solanum lycopersicum). Previously, we have reported that the tomato EIN2‐like protein YELLOW‐FRUITED TOMATO1 (YFT1), a core component in the ethylene signal transduction pathway, exerts a critical regulatory function in the tomato fruit ripening process.
Tengjian Wen   +3 more
wiley   +1 more source

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