Results 61 to 70 of about 7,225 (131)

Integrative chromosome‐scale genome analysis of cupuassu provides insights into witches' broom disease resistance and expands genomic resources for Theobroma

open access: yesThe Plant Genome, Volume 19, Issue 1, March 2026.
Abstract Cupuassu (Theobroma grandiflorum) is a fruit tree native to the Brazilian Amazon and increasingly relevant to regional bioeconomies. Its cultivation is severely affected by witches’ broom disease (WBD), caused by Moniliophthora perniciosa. While a chromosome‐scale genome of the susceptible genotype C1074 is available, the lack of a resistant ...
Vinicius A. C. de Abreu   +8 more
wiley   +1 more source

Genomic Sequencing and Analysis of New Variants of Enzootic Nasal Tumour Virus Type 2 Revealed Recombination Events between Different Sublineages

open access: yesVeterinary Medicine and Science, Volume 12, Issue 2, March 2026.
The strains from sublineages 1.5 and 1.2 may be promoting the emergence of new strains of ENTV‐2 in China. Recombination drives ENTV‐2's rapid evolution . ABSTRACT In recent years, multiple regions in China have experienced an increase in the occurrence of enzootic nasal tumour virus type 2 (ENTV‐2) infections. This research highlights the initial full
Yong Pan   +5 more
wiley   +1 more source

Sex‐Specific doublesex Regulation Targeting the Color‐Patterning Gene h Underlies the Evolution of Wing Sexual Dimorphism in the Harlequin Ladybug Harmonia axyridis

open access: yesEvolution &Development, Volume 28, Issue 1, March 2026.
doublesex regulates sexual dimorphism in elytral color patterns of Harmonia axyridis by downregulating the color patterning gene h in males. This regulatory link diverged in derived color morphs, coinciding with the loss of sex‐specific elytral color patterns.
Soichi Yeki   +7 more
wiley   +1 more source

DNA Methylation Episignature as a Novel Diagnostic Tool for Diamond‐Blackfan Anemia Syndrome

open access: yesAmerican Journal of Hematology, Volume 101, Issue 2, Page 228-241, February 2026.
Diamond‐Blackfan Anemia Syndrome (DBAS) is a congenital bone marrow failure disorder characterized by defective erythropoiesis and a spectrum of congenital anomalies, including craniofacial malformations, limb abnormalities, and cardiac and renal defects.
Paola Quarello   +29 more
wiley   +1 more source

Progress in RNA‐Targeted Therapeutics for Human Diseases

open access: yesMedComm, Volume 7, Issue 2, February 2026.
RNA‐targeted therapies are revolutionizing molecular medicine by transitioning from a “protein‐centric” focus to an “RNA‐regulatory network” approach. Leveraging RNA's diverse roles in gene regulation, signaling, and epigenetic modifications, advanced platforms such as ASOs, siRNA, miRNA, mRNA, aptamers, shRNA, and CRISPR/Cas systems are enabling ...
Wangzheqi Zhang   +10 more
wiley   +1 more source

Distinct 5′ UTR Requirements for Translation of the Bicistronic X/P mRNA Among Avian Orthobornaviruses

open access: yesMicrobiology and Immunology, Volume 70, Issue 2, Page 80-90, February 2026.
ABSTRACT Orthobornaviruses express X and the phosphoprotein (P) from a bicistronic X/P mRNA, and these proteins regulate polymerase activity. In mammalian orthobornaviruses, the 5′ untranslated region (5′ UTR) of the X/P mRNA controls the translational balance between X and P and thereby promotes efficient replication.
Meng‐Chi Wu   +7 more
wiley   +1 more source

Loss of E3 ligase HvST1 function substantially increases distal crossover frequency

open access: yesNew Phytologist, Volume 249, Issue 3, Page 1325-1341, February 2026.
Summary This study characterizes the function of a grass‐specific E3 ubiquitin ligase, HvST1, in regulating synapsis and crossover (CO) formation during meiosis in barley (Hordeum vulgare). In large‐genome cereals, COs are predominantly restricted to distal chromosomal regions, limiting genetic recombination and breeding flexibility.
Jamie Neil Orr   +8 more
wiley   +1 more source

Impact of BoLA‐DRB3 Polymorphisms on Clonality of Bovine Leukaemia Virus‐Infected Cells of Cattle With Lymphoma

open access: yesHLA, Volume 107, Issue 2, February 2026.
ABSTRACT Bovine leukaemia virus (BLV) infects cattle, integrates into the host genome as a provirus, and induces a persistent infection that remains asymptomatic but can cause leukaemia/lymphoma. Most BLV‐infected cell clones are created by massive depletion, and a few of these infected cell clones expand through the mitotic cycle, leading to the onset
Noriko Fukushi   +10 more
wiley   +1 more source

Investigating and correcting a rare pathogenic mutation in GDF11. [PDF]

open access: yesHGG Adv
Congdon ST   +9 more
europepmc   +1 more source

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