Results 161 to 170 of about 918,085 (317)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Salvage After Patient-Driven Delayed Conversion From External Fixation to Intramedullary Nailing in an Open Tibial Shaft Fracture: A Case Report. [PDF]

Case Rep Orthop
Sulaiman M.
europepmc   +1 more source

Biological Nitrogen Fixation and Plant-Associated Microorganisms

, 2010
xxiii, 270 p.National Meeting of the Spanish Society of Nitrogen Fixation (SEFIN) (13th. Zaragoza. 2010)This book contains the contributions presented at the XIII National Meeting of the Spanish Society of Nitrogen Fixation (SEFIN) and II Portuguese ...
González-Andrés,Fernando, Portuguese-Spanish Congress on Nitrogen Fixation (2nd. Zaragoza. 2010)   +1 more
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Early postoperative pain and quality of life with different modalities of mesh fixation in laparoscopic trans-abdominal pre-peritoneal repair of inguinal hernia: a randomized controlled trial. [PDF]

BMC Surg
Aziz AE, Khalil AH, Abdelnasser A, Elmonim AMA.   +3 more
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Dorsal bridge plating, volar plating, or both? A retrospective analysis of clinical and radiographic outcomes of intraarticular distal radius fracture fixation techniques. [PDF]

Eur J Orthop Surg Traumatol
Litten R, Wilson A, Yeager M, Rutz R, McIlwain R, Frith K, Quade J.   +6 more
europepmc   +1 more source

Effect of combined nitrogen on symbiotic nitrogen fixation in pea plants

, 1979
The nitrogen-fixing activity of the symbiotic system of Pisum sativum with Rhizobium leguminosarum is adversely affected by combined nitrogen. Both ammonium chloride and potassium nitrate, when added to the roots, lower the nitrogenase activity ...
Houwaard, F.
core  

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Near Fixation-Associated Intraocular Pressure Reduction in Intermittent Exotropia: Postoperative Changes After Strabismus Surgery. [PDF]

Clin Ophthalmol
Suzuki T, Fukutome T, Otaki C, Ueta Y, Suzuki T.   +4 more
europepmc   +1 more source