Integrated light and electron microscopy workflow for morphological, molecular and ultrastructural analysis of spheroids. [PDF]
Tratnjek L +4 more
europepmc +1 more source
Pss knockdown in the midgut causes growth retardation in Drosophila similar to that in human LMHD
Abstract Background Phosphatidylserine synthase (PSS), localized in the mitochondrial membrane, synthesizes phosphatidylserine. In humans, mutations in Pss lead to Lenz–Majewski hyperostotic dwarfism, a disorder affecting growth and development. The effects of Pss mutations on the growth of Drosophila melanogaster are not fully known. Hence, this study
Kwan‐Young Kim +4 more
wiley +1 more source
Assessing PD-L1 expression in non-small cell lung carcinoma: a prospective study of matched fine-needle aspirates, core biopsies, and resection specimens using alcohol and forming fixatives. [PDF]
Haragan A +5 more
europepmc +1 more source
Abstract Background Previous experiments inducing leakage of embryonic cerebrospinal fluid (CSF) suggest the necessity of intraventricular CSF pressure (PCSF) for brain morphogenesis. Nevertheless, how embryonic PCSF occurs is unclear, especially in utero. Results Using a Landis water manometer, we measured PCSF in fetal mice isolated from the amniotic
Koichiro Tsujikawa +2 more
wiley +1 more source
Optimizing core needle biopsy specimen collection techniques to enhance molecular testing adequacy in non-small cell lung cancer. [PDF]
Lin Z +15 more
europepmc +1 more source
Aqueous zinc–iodine batteries (Zn–I2Bs) offer promise for grid storage due to safety and cost advantages yet face critical bottlenecks: severe self‐discharge (polyiodide shuttling and HER), limited energy density, sluggish kinetics, and zinc anode instability.
Jia‐Lin Yang +3 more
wiley +1 more source
Introducing the Dish Soap Protocol: A Unified Approach for Multi-Modal Intracellular Staining. [PDF]
Burton OT, Dooley J, Liston A.
europepmc +1 more source
Long‐lasting remodeling of astrocytes in an Scna1+/− mouse model of Dravet syndrome
Abstract Objective Dravet syndrome (DS) is a prototypical developmental and epileptic encephalopathy caused by mutations in the SCN1A gene, leading to loss of function of the voltage‐gated sodium channel Naᵥ1.1. The latter causes early onset drug‐resistant seizures and enduring cognitive and behavioral deficits.
Athénaïs Genin +10 more
wiley +1 more source
Looking Back to Move Forward: Tannic Acid in TEM of Parasitic Protozoa. [PDF]
Ortiz S, de Souza W, Benchimol M.
europepmc +1 more source
Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz +9 more
wiley +1 more source

