Results 131 to 140 of about 93,969 (292)

Innovative Metasurface Colorimetric Cell‐on‐a‐Chip Sensor for Continuous, Label‐Free, Non‐Destructive Assessment of Intestinal Barrier Dynamics

Advanced Science, EarlyView.
We developed a real‐time, label‐free, high‐throughput cell‐on‐a‐chip system based on a metasurface plasmon resonance colorimetric sensor (MetaSPRCS) to evaluate intestinal barrier function. This platform enables continuous monitoring of cell adhesion, proliferation, and barrier layer formation, disruption, and repair.
Youqian Chen, Wen Li, Jiaying Feng, Yue Shu, Yihui Yang, Yuyan Wang, Rui Li, Hanlin Zhou, Xinfan Yang, Yuxue Guo, Mingqian Chen, Wenjun Hu, Gang Logan Liu, Liping Huang, Yanan Li   +14 more
wiley   +1 more source

Porcine intestinal mast cells. Evaluation of different fixatives for histochemical staining techniques considering tissue shrinkage

, 2013
Juliane Rieger, Sven Twardziok, H. Huenigen, Ruth M. Hirschberg, Johanna Plendl   +4 more
openalex   +2 more sources

Lactylation Reprogramming in the Bone Infection Microenvironment Identifies PGK1 K361 as a Potential Therapeutic Target for Osteogenic Dysfunction

Advanced Science, EarlyView.
Staphylococcus aureus (S. aureus) infection creates a high‐lactate microenvironment, promoting p300‐mediated lactylation of PGK1 at lysine 361 (K361). Lactylated PGK1 translocates to the mitochondrial outer membrane and interacts with VDAC3. This interaction triggers FtMt downregulation, iron accumulation, and excessive PINK1/Parkin‐mediated mitophagy,
Han‐jun Qin, Si‐ying He, Ting‐hui Xiao, Da‐mao Dai, Xin‐jia Hu, Nan Jiang   +5 more
wiley   +1 more source

Adropin modulates pancreatic cell proliferation and glutathione levels in an animal model of type 1 diabetes mellitus

Animal Models and Experimental Medicine, EarlyView.
Adropin is related to the energy homeostasis‐associated gene. It significantly increased glutathione reductase enzyme levels in the pancreas of experimental diabetic rats. Adropin may reduce the severity of diabetes and its complications. Cell proliferation in the exocrine is reduced after the administration of adropin.
Ifrah I. Ali, Crystal D'Souza, Abderrahim Nemmar, Shreesh Ojha, Ernest A. Adeghate   +4 more
wiley   +1 more source

Patient-reported outcomes after hemorrhoid surgery: early results from a prospective, nationwide, real-world, cohort study on diverse approaches. [PDF]

Ann Coloproctol
Kement M, Tekin A, Baysal H, Tosun S, Alimoğlu O, Sücüllü İ, Civil O, Sakoğlu N, Arslan NÇ, Tatar C, Naycı AE, Arı A, Çakır E, Kaya R, Turan İ, Gülşen T, Meriç S, Yavuz E, Buğdaycı N, Hamad FM, Leventoğlu S, Kozan R, Akpınar Ö, Yanar H, Yanar F, Küçük HF, Karahan M, Kaya S, Adıgüzel NC, Önder T, Abcı İ, Aydın AZ, Özkan ÖF, Kızıltoprak N, Özcan B, Orhan A, Cantürk AÖ, Tan M, Bilgin Y, Çok H, Cezit A, Fersahoğlu MM, Öncel M.   +42 more
europepmc   +1 more source

Reassessment of the rate of fixative diffusion. [PDF]

, 1992
R D Start, Chris Layton, Simon S. Cross, JA Smith   +3 more
openalex   +1 more source

Zinc and Strontium‐Doped Titania Nanotube Surfaces Enhance Antibacterial Activity and Increase Osteogenic Differentiation of Mesenchymal Stem Cells

Advanced NanoBiomed Research, EarlyView.
Bacterial infection and poor integration often lead to orthopedic implant failure. Modifying implant surfaces can improve osseointegration. Titanium has been engineered to form titania nanotubes doped with zinc and strontium. These surfaces were evaluated for antibacterial effects and their ability to promote osteogenic differentiation in stem cells ...
Abhishek Bhattacharjee, Aniruddha Vijay Savargaonkar, Bruno L. Pereira, Paulo Soares, Ketul C. Popat   +4 more
wiley   +1 more source

Solvent-induced partial cellular fixation decodes proteome-wide drug targets and downstream pathways in living cells. [PDF]

Nat Commun
Yu T, Wang Y, Wang K, Fang Z, Zhu H, Zhang X, Li Y, Ye M.   +7 more
europepmc   +1 more source

Abstract 2470 Characterizing safer chemical fixatives for fluorescence microscopy in budding yeast

D.L. Cheney, Mary James, Kevin Suh, Verónica A. Segarra   +3 more
openalex   +1 more source

Expanded application to plant reproductive tissues of a branched DNA probe‐based in situ hybridization method

Applications in Plant Sciences, EarlyView.
Abstract Premise Detecting clear tissue‐ and organ‐specific patterns of gene expression is key to understanding the genetic mechanisms that control plant development. In situ hybridization (ISH) of mRNA is one of the most precise, yet most challenging approaches to gene expression assays.
Brooklyn M. Anaya, Austin T. Nguyen, Kelly K. S. Matsunaga, Lena C. Hileman   +3 more
wiley   +1 more source