Results 121 to 130 of about 150,410 (356)

No Easy Fixes [PDF]

open access: yesNew England Journal of Medicine, 2013
Ms. D. has received 10 drug-eluting stents, primarily for atypical chest discomfort, with one stenting begetting another. In our system, it's somehow easier to provide 10 state-of-the-art stents than access to a generic pill and social, financial, and psychiatric support.
openaire   +2 more sources

PRMT5/Sohlh2/Sirt1 Signaling Pathway in Vascular Endothelial Cells Modulates Lung Metastasis of Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
The cover image shows that vascular endothelial cells play an important role in lung metastasis of TNBC. Endothelial Sohlh2 acts as a gatekeeper against TNBC lung metastasis by limiting endothelial activation and tumor cell passage. PRMT5 reduces Sohlh2 stability, weakening this protective barrier.
Ruihong Zhang   +8 more
wiley   +1 more source

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

open access: yesHepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario   +12 more
wiley   +1 more source

To fix or not to fix? [PDF]

open access: yesJournal of Musculoskeletal Surgery and Research, 2019
openaire   +3 more sources

Trained Memory of Uterine Macrophages Improves Subsequent Pregnancy Outcomes

open access: yesAdvanced Science, EarlyView.
This study identifies that pregnancy imprints a durable, pregnancy‐specific form of trained immune memory in uterine macrophages, marked by the emergence of LILRB3+/PIR‐B+ cells that expand across gestations, acquire a tolerogenic and metabolically rewired phenotype, and actively protect against inflammatory pregnancy loss in mice.
Jing Wang   +8 more
wiley   +1 more source

Projection transparencies from printed material [PDF]

open access: yes, 1968
Method for preparing project transparencies, or view graphs, permits the use of almost any expendable printed material, pictures, charts, or text, in unlimited color or black and white.
Grunewald, L. S., Nickerson, T. B.
core   +1 more source

TopCas: Topology‐Gated Cas12a via DNA‐RNA Chimeric Circular crRNA for Amplification‐Free Nucleic Acid Detection and Conditional Gene Editing

open access: yesAdvanced Science, EarlyView.
The TopCas platform utilizes an engineered DNA‐RNA chimeric circular crRNA to establish topology‐gated control over CRISPR‐Cas12a activity, enabling target‐triggered self‐catalytic amplification (preamplification‐free). This system seamlessly integrates highly sensitive molecular diagnostics with conditionally controlled gene editing, demonstrating ...
Shun Zhang   +7 more
wiley   +1 more source

Fixation of virgin lunar surface soil [PDF]

open access: yes
Two systems are shown to be suitable for fixing loose particulate soils with a polymer film, without visually detectable disturbance of the soil particle spatial relationships.
Cannon, W. A., Conley, J. M., Frazer, R.
core   +1 more source

Oxidative stress and bone markers in plasma of patients with long-bone fixative surgery: Role of antioxidants [PDF]

open access: bronze, 2010
A. Sandukji   +4 more
openalex   +1 more source

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