Application of alternative fixatives to formalin in diagnostic pathology [PDF]
European Journal of Histochemistry, 2012 Fixation is a critical step in the preparation of tissues for histopathology. The objective of this study was to investigate the effects of different fixatives vs formalin on proteins and DNA, and to evaluate alternative fixation for morphological ...
L. Benerini Gatta +8 more
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Comparison of histomorphology and DNA preservation produced by fixatives in the veterinary diagnostic laboratory setting [PDF]
PeerJ, 2014 Histopathology is the most useful tool for diagnosis of a number of diseases, especially cancer. To be effective, histopathology requires that tissues be fixed prior to processing.
William F. Craft +2 more
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PLoS ONE, 2020 Bacterial biofilms are organized sessile communities of bacteria enclosed in extracellular polymeric substances (EPS). To analyze organization of bacteria and EPS in high resolution and high magnification by scanning electron microscopy (SEM), it is ...
Rohana P Dassanayake +5 more
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A Field‐Friendly, Non‐Toxic Fixative for Integrated Morphological and Molecular Research in Non‐Model Invertebrates [PDF]
Ecology and EvolutionFormalin, ethanol, and RNAlater are the most commonly used fixatives for morphological and molecular studies. Formalin is preferred for preserving tissue morphology, whereas ethanol and RNAlater are used to obtain high‐quality nucleic acids for molecular
Irene delOlmo +3 more
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Comparative Analysis of Davidson and Glyoxal Fixatives on Autofluorescence and Immunolabeling in Medaka (Oryzias latipes) Tissues [PDF]
BiomedicinesBackground: Fixation influences the quality of staining across species, especially in neuroscience, where accurate visualization of neuronal structures and protein localization is crucial for understanding brain function and pathology.
Li Xiao +5 more
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Evaluation of Formalin Substitution Fixative Effects on H & E Staining Results [PDF]
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2012 Background and Objectives: These days, Formalin is considered as a good and cheap fixative, but very harmful for human health. It is one of chemical components which has traditionally been used as a routine fixative in anatomy and pathology laboratories;
A Anissian, M Eidi
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Effect of tissue fixatives on the corrosion of biomedical magnesium alloys [PDF]
HeliyonIn this work, the corrosion behavior of pure Mg, Mg3Ag, Mg6Ag, and MgZnYNd alloys in different fixatives (ethyl alcohol (EA), 85 % ethyl alcohol (85 % EA), 10 % neutral buffered formalin (10 % NBF), 4 % glutaric dialdehyde (4 % GD), and 4 ...
Guanqi Liu +6 more
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Effect of Fixatives and Fixation Period on Morphology and Immunohistochemistry of Feline Ovarian Tissue [PDF]
AnimalsFixatives and fixation protocol have a profound effect on both the morphology and epitope sensitivity of ovarian tissue, which hampers accurate ovarian tissue evaluation.
Isa Mohammed Alkali +4 more
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ALTERATION OF THE CONFORMATION OF PROTEINS IN RED BLOOD CELL MEMBRANES AND IN SOLUTION BY FIXATIVES USED IN ELECTRON MICROSCOPY [PDF]
Journal of Cell Biology, 1968 John Lenard
exaly +2 more sources
MRIMS Journal of Health SciencesBackground: Formal saline is an extensively used cheapest and easily available tissue fixative. However, formalin has been proven to have carcinogenic effects.
Lakshya Venugopal, Vasudha Kulkarni
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