Results 41 to 50 of about 11,465 (303)

Impact of standardization in tissue processing: the performance of different fixatives [PDF]

open access: yes, 2022
Most tissues in clinical practice are formalin-fixed and paraffin-embedded for histological as well as molecular analyses. The reproducibility and uniformity of molecular analyses is strictly dependent on the quality of the biomolecules, which is highly ...
De Martino, Eleonora   +9 more
core   +1 more source

Methanol fixation for scanning electron microscopy of plants

open access: yesApplied Microscopy, 2020
Plant specimens for scanning electron microscopy (SEM) are commonly treated using standard protocols. Conventional fixatives consist of toxic chemicals such as glutaraldehyde, paraformaldehyde, and osmium tetroxide.
Ki Woo Kim
doaj   +1 more source

A study of wood resin and cationic water soluble polymers : wood pitch fixatives [PDF]

open access: yes, 2008
The deposition of wood resins (i.e. wood pitch, or pitch) has been a problem for the pulp and paper industry for many years. Unfortunately wood pitch fixatives do not eliminate wood resin deposition all of the time.
McLean, DS (15502571)
core   +1 more source

FIXATIVES AND FIXATION PROTOCOLS: COMPARATIVE ANALYSIS OF TECHNIQUES FOR LIGHT MICROSCOPY AND DOWNSTREAM FUNCTIONAL CONSERVATION [PDF]

open access: yes, 2020
This thesis purports to provide a comprehensive review of fixatives and fixation techniques for the purpose of light microscopy, and for the various downstream processes that may occur during or after microscopic visualization.
Moore, Caito
core  

The Pathologist’s Guide to Fixatives [PDF]

open access: yes, 2014
Proper tissue fixation is essential to ensure the highest level of specimen evaluation. Pathologists and laboratory staff are frequently consulted by clinical counterparts regarding what fixative should be used for different tissues or to enable a ...
Christina E. Day   +5 more
core   +1 more source

Comparative usefulness of tissue fixatives for in situ viral nucleic acid hybridization. [PDF]

open access: yes, 1985
Traditionally tissues for in situ hybridization of viral nucleic acid have been small pieces obtained from laboratory rodents, and fixatives that are designed for electron microscopy, such as periodate-lysine-paraformaldehyde (PLP) can handle them ...
H A McAllister, D L Rock
core   +1 more source

Effects of Different Fixatives on β-Galactosidase Activity [PDF]

open access: yes, 2002
β-Galactosidase (β-Gal) staining is widely used to demonstrate specific gene expression during evaluation of gene targets in vivo. This technique is extremely sensitive to fixation.
Berton Zbar   +3 more
core   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Quantitative Comparison of Immunohistochemical Staining Intensity in Tissues Fixed in Formalin and Histochoice

open access: yesAnalytical Cellular Pathology, 1997
Formaldehyde fixatives have traditionally been used to preserve tissues as they impart excellent morphological preservation. Formaldehyde fixes tissue by cross linking, a process which can reduce the antigenicity of tissue and weakens the intensity of ...
D. Geoffrey Vince   +5 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

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