The specificity and patterns of staining in human cells and tissues of p16INK4a antibodies demonstrate variant antigen binding [PDF]
The validity of the identification and classification of human cancer using antibodies to detect biomarker proteins depends upon antibody specificity. Antibodies that bind to the tumour-suppressor protein p16INK4a are widely used for cancer diagnosis and
A Melck +34 more
core +3 more sources
An unusual preparation of an eighteenth-century spider and its consequences [PDF]
Investigation into an eighteenth-century spider in the collection of The Hunterian Museum, Glasgow, revealed an unusual and intriguing mounting method for a natural history specimen.
Brown, Georgina, Hancock, E. Geoffrey
core +1 more source
Ischemic Mitral Regurgitation: To Fix or Not to Fix [PDF]
Abstract Optimal interventional planning for ischemic mitral regurgitation, initially known as papillary muscle dysfunction syndrome, has been a matter of debate for decades. The primary challenge constitutes the selection of patients who will benefit from an intervention.
Huma, Fatima +4 more
openaire +2 more sources
“Fecal microbiome in epidemiologic studies” - Letter [PDF]
We congratulate Sinha et al. on their recent report (1) comparing fecal sample collection methods for epidemiologic studies of the gut microbiome. These data contribute to the increasing body of literature describing robust methodological frameworks for ...
Abu-Ali, Galeb +5 more
core +2 more sources
Introduction: Liquid-based cytology (LBC) has been widely used since 2000. Next-Generation Sequencing (NGS) analysis of residual specimens in LBC fixative may also be performed for pancreatic cancer in the near future.
Junya Izuhara, Kazuki Kanayama
doaj +1 more source
Intimal and medial contributions to the hydraulic resistance of the arterial wall at different pressures: a combined computational and experimental study [PDF]
The hydraulic resistances of the intima and media determine water flux and the advection of macromolecules into and across the arterial wall. Despite several experimental and computational studies, these transport processes and their dependence on ...
Chooi, KY +3 more
core +2 more sources
The elasticity of biological tissues is one of the physical characteristics of tissues and has attracted attention as a clinical diagnostic parameter. The elasticity can be determined on the microscopic scale with speed of sound (SoS) measurements using ...
Kazuki Tamura +5 more
doaj +1 more source
Monoclonal antibodies against human astrocytomas and their reactivity pattern [PDF]
The establishment of hybridomas after fusion of X63-Ag8.653 mouse myeloma cells and splenocytes from mice hyperimmunized against human astrocytomas is presented. The animals were primed with 5 × 106 chemically modified uncultured or cultured glioma cells.
B. Martin +36 more
core +1 more source
Crescent and star shapes of members of the Chlamydiales order: impact of fixative methods. [PDF]
Members of the Chlamydiales order all share a biphasic lifecycle alternating between small infectious particles, the elementary bodies (EBs) and larger intracellular forms able to replicate, the reticulate bodies.
Aeby, S. +5 more
core +2 more sources
Biochemical, electron microscopic and immunohistological observations of cationic detergent-extracted cells: detection and improved preservation of microextensions and ultramicroextensions [PDF]
Background Filopodia, retraction fibers and microvilli, are fragile microextensions of the plasma membrane that are easily damaged by mechanical force during specimen preparation for microscopy.
Nakamura Fumihiko
core +1 more source

