Results 161 to 170 of about 158,082 (381)

Spatiotemporal Transcriptomic Atlas Reveals the Regulatory Mechanisms Underlying Early Inflorescence Development and Sex Differentiation in Spinach

open access: yesAdvanced Science, EarlyView.
High‐resolution spatiotemporal transcriptomic data from male and female spinach inflorescences across four key stages first reveal the sex differentiation initiates at the four‐leaf stage and is governed by epigenetic regulation via the SpMSI1‐SpHDT2 complex.
Chen You   +10 more
wiley   +1 more source

Heme/NADH Mimics Co‐Decorated Allosteric Capsules for Regulating Oxygen Activation and Upregulating Intracellular Methionine Depletion

open access: yesAdvanced Science, EarlyView.
Through modifying the switchable µ‐oxo bridged FeIII‐porphyrins moiety and NADH mimics into a metal‐organic capsule, multiple responsive manners for O2 activation, chemical oxygenation and metabolic transformation have been demonstrated for upregulating intracellular methionine depletion and accumulation of methionine sulfoxide to achieve effective ...
Chunming Ma   +5 more
wiley   +1 more source

COMPARISON OF FIXATIVES AND SUBSTRATES FOR AMINOPEPTIDASE [PDF]

open access: bronze, 1965
Benito Monis   +2 more
openalex   +1 more source

FOXM1 Protects Against Myocardial Ischemia‐Reperfusion Injury in Rodent and Porcine Models by Suppressing MKRN1‐Dependent LKB1 Ubiquitination

open access: yesAdvanced Science, EarlyView.
FOXM1 maintains mitochondrial bioenergetic function by inhibiting MKRN1‐mediated ubiquitination of LKB1 in cardiomyocytes. Loss of FOXM1 in cardiomyocytes results in upregulation of MKRN1, which enhances LKB1 ubiquitination and disrupts AMPK signaling and energy metabolism pathways. Conversely, FOXM1 overexpression preserves mitochondrial bioenergetics
Shuai Song   +17 more
wiley   +1 more source

Effect of Bazi Bushen Capsule on D‐Galactose‐Induced Human Endothelial Cell Senescence Through PI3K/Akt/eNOS Signaling Pathway

open access: yesAGING MEDICINE, Volume 8, Issue 3, Page 258-266, June 2025.
Bazi Bushen capsule (BZBS) is an over‐the‐counter drug approved by China FDA with the function of nourishing the kidney, replenishing essence, and combating aging. In this study, we concluded that the PI3K/AKT/eNOS signaling pathway contributed to BZBS repair of endothelial dysfunctions induced by D‐galactose.
Lulu Yao   +6 more
wiley   +1 more source

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