Results 171 to 180 of about 95,582 (265)

Overexpressed Spindlin1 relocalizes to the nucleoli during fixation. [PDF]

Biochem Biophys Rep
Fischer FI, Pervetica A, Moeser M, Morgenthal S, Kugler J.   +4 more
europepmc   +1 more source

Assessing Metabolic and Reproductive Consequences of Prenatal Paracetamol Exposure in Female CD1 Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Paracetamol is a widely used analgesic during pregnancy; however, emerging evidence suggests it may act as an endocrine/metabolism disrupting compound. Using an F1 female CD1 mouse model, this study scrutinized the long‐term metabolic and reproductive consequences linked to intrauterine paracetamol exposure.
Bita Entezari, Deniz Bozdag, Elif İnce‐Erguc, Aylin Buhur, Cansin Sirin Tomruk, Suna Sabuncuoglu, Altug Yavasoglu, Hande Gurer‐Orhan   +7 more
wiley   +1 more source

Advancing human ovarian biology in tandem with clinical care: considerations for collecting ovarian tissue for research after oophorectomy for tissue cryopreservation. [PDF]

Front Endocrinol (Lausanne)
Brunette MA, Burns K, Hoefgen H, Xiao S, Duncan FE, Laronda MM, Shikanov A, Zelinski M, Gomez-Lobo V.   +8 more
europepmc   +1 more source

Improving protein secretion with autophagy‐inhibiting or proteasome‐activating small molecules

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Therapeutic proteins are produced frequently by mammalian cells in large‐scale bioreactors. As a result, producer cells are exposed to a chemically (nutrients, gas exchange, target protein overexpression) and physically (shear due to mixing) stressful environment, which can lead to endoplasmic reticulum (ER) stress and loss of ...
R Chauncey Splichal, Christina Chan, S Patrick Walton   +2 more
wiley   +1 more source

Transmission electron microscopy characterisation of Spirulina bioplastics. [PDF]

J Microsc
Azidhak S, Taatjes DJ, Campbell IR, Roumeli E, Schadler LS.   +4 more
europepmc   +1 more source

PRDM1 Knockdown Promotes Ferroptosis and Sunitinib Sensitivity by Modulating the PI3K/Akt Signaling Through Inhibition of ESM1 Transcription in Renal Cell Carcinoma

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Renal cell carcinoma (RCC) is a commonly occurring and considerable burden on public health. Although chemotherapy benefits patients with advanced RCC, sunitinib resistance leads to a poor prognosis. Ferroptosis is also involved in sunitinib resistance in RCC.
Yi‐Shuai Zhang, Xin‐Qi Pei, Ji‐Ping Sun, Chen‐Hui Ma, Xin‐Yang Wang, Xu‐Dong Li   +5 more
wiley   +1 more source

Microbial biomining from asteroidal material onboard the international space station. [PDF]

NPJ Microgravity
Santomartino R, Rodriguez Blanco G, Gudgeon A, Hafner JH, Stirpe A, Waterfall M, Cayzer N, Pichevin L, Calder G, Birkenfeld KR, Waajen AC, McLaughlin S, Mariani A, Balsamo M, Neri G, Eades LJ, Cockell CS.   +16 more
europepmc   +1 more source

From the sea to DNA barcode: Optimized preservation method for gelatinous zooplankton integrative taxonomy

Limnology and Oceanography: Methods, EarlyView.
Abstract Assigning taxonomic identity and thus assessing taxonomic diversity in gelatinous zooplankton is challenging due to their fragility and difficult preservation. Formalin fixation compromises DNA integrity, while flash‐freezing, ethanol, and acetone preservation affect morphological features. In this study, we developed a methodological protocol
Claudia Traboni, Rade Garić, Rita Marino, Paolo Sordino, Priscilla Licandro   +4 more
wiley   +1 more source

Protocol for ultrafast immunolabeling and 3D imaging of whole organs and large tissues. [PDF]

STAR Protoc
Ding Z, Liu H, Chen J, Kusumbe AP.
europepmc   +1 more source

Effects of preservatives and poisons on the elemental and isotopic composition of freshwater particulate organic matter

Limnology and Oceanography: Methods, EarlyView.
Abstract Sediment traps, often used in tandem with preservatives or poisons, are widely used for the collection of particulate organic matter (POM), providing insight into the source to sink mechanisms that shape major biogeochemical cycles and sedimentary carbon sequestration.
Diana Velazquez, Nathan D. Sheldon, Jenan J. Kharbush   +2 more
wiley   +1 more source