Results 211 to 220 of about 93,969 (292)

Bridging the Effects of Noncontact Temperature Sensing and Cellular Biofunctionality in Nanosized Dysprosium(III)‐Doped Fluorapatite

open access: yesSmall, EarlyView.
Multifunctional dysprosium(III) ion–doped fluorapatite nanomaterials combine bioactivity with photoluminescent temperature sensing. The biological studies reveal interactions with progenitor cells, highlighting potential applications in regenerative medicine and tissue engineering, while temperature‐dependent emission of Dy³⁺ ions enables reliable ...
Sara Targonska   +7 more
wiley   +1 more source

Renovating Neural Networks With Viral‐Mediated Gene Transfer From A Tissue Contacting Matrix Mimic

open access: yesSmall, EarlyView.
Fmoc‐DDIKVAV self‐assembling peptidemediated delivery of AAV‐BDNF significantly enhances neuroprotection in the striatum of a mouse model compared with AAV‐BDNF injection alone. This synergistic integration of biomaterial scaffolding and gene therapy holds substantial promise for slowing the progression of neurodegenerative diseases such as Huntington ...
Shiva Soltani Dehnavi   +11 more
wiley   +1 more source

Brain Pericytes and Wnt/β‐Catenin Signaling Induce Functional Blood–Brain Barrier Phenotype in Human iPSC‐Derived Model

open access: yesSmall Methods, EarlyView.
This study shows that human iPSC‐derived endothelial cells acquire a functional blood–brain barrier phenotype when co‐cultured with brain pericytes and stimulated with CHIR‐99021, a Wnt/β‐catenin activator. This model recapitulates key barrier properties, inflammatory responses, and transcriptomic features of the native human BBB, offering new ...
Henrique Nogueira Pinto   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy