Image Analysis Platform for Comprehensive Quantification of Extracellular Vesicle Morphology
ABSTRACT Extracellular vesicles (EVs) are membrane‐encapsulated nanoparticles with key roles in cell biology and growing importance in biomedicine. However, EVs are challenging to characterize because they are highly heterogeneous. Single EV analysis methods are valuable tools for addressing this challenge.
Alexander Spark +7 more
wiley +1 more source
A Practical Approach to Study Uncultivated Protists Using Single-Cell Techniques for Electron Microscopy. [PDF]
Palka MV +4 more
europepmc +1 more source
Safety Evaluation of an Aqueous Root and Leaf Extract of Ashwagandha (Withania somnifera)
Sensoril, an aqueous root and leaf extract of ashwagandha showed no evidence of mutagenicity in the in vitro Ames assay, was negative in the in vitro micronucleus, in vivo mammalian bone marrow chromosome aberration assays, and was well tolerated in the rat at up to 4000 mg/kg BW/day when administered orally for a period of 90 days. The data from these
Mukesh Summan +2 more
wiley +1 more source
Microbial biomining from asteroidal material onboard the international space station. [PDF]
Santomartino R +16 more
europepmc +1 more source
Advanced design and application for viologen‐based redox devices with customizable functionalities
This review examines viologen‐based materials with customizable functionalities achieved through molecular engineering strategies such as side‐chain modification and composite formation. It emphasizes their utility in electrochromic devices, multicolor displays, and energy storage, while discussing stability challenges and outlining future development ...
Yuxin Chang +7 more
wiley +1 more source
Assessing PD-L1 expression in non-small cell lung carcinoma: a prospective study of matched fine-needle aspirates, core biopsies, and resection specimens using alcohol and forming fixatives. [PDF]
Haragan A +5 more
europepmc +1 more source
Untreated Hair Dye Effluents Enter the Environment: Are They a Threat to Human Health?
ABSTRACT The effluents generated during the process of hair dyeing exhibit a complex composition, comprising chemical compounds with varying toxicity levels. While the adverse impact of hair dyes on human health is acknowledged, there is a notable absence of studies addressing the toxicity associated with effluents produced during these activities. The
Letícia Cristina Gonçalves +3 more
wiley +1 more source
Optimized Whole-Mount X-gal Staining to Detect Hedgehog Signaling Activity in Basal Cell Carcinoma: A Platform for Spatial Integration with Immune Analysis. [PDF]
Wang H, Zhu Y, Kim AL.
europepmc +1 more source
Acrolein as a fixative for enzyme cytochemistry. [PDF]
T. Saito, Hiromi Keino
openalex +1 more source
PHF1 is a known epigenetic regulator involved in transcriptional silencing in cancer. In this study, we identified PHF1 as an oncogene that promotes PDAC progression and demonstrated that its inhibition induces ferroptosis. Mechanistically, PHF1 physically interacts with the FBL/NOP56/NOP58 snoRNP complex to enhance the IRES‐dependent translation of ...
Yujiao Xie +9 more
wiley +1 more source

